Results 51 to 60 of about 30,715 (166)

Demyelination-induced glutamatergic imbalance mediates hippocampal Hyperexcitability

open access: yesNeurobiology of Disease
Chronic demyelination is a hallmark of multiple sclerosis (MS) and is associated with increased seizure susceptibility. In this study, we used the cuprizone (CPZ) diet induced demyelination model to investigate the progression of hippocampal ...
Alyssa M. Anderson   +9 more
doaj   +1 more source

The metabolic reprogramming of γ-aminobutyrate in oral squamous cell carcinoma

open access: yesBMC Oral Health
Oral squamous cell carcinoma (OSCC) is the most common head and neck malignancy. The oncometabolites have been studied in OSCC, but the mechanism of metabolic reprogramming remains unclear.
Shi-Lian Wu   +4 more
doaj   +1 more source

Transcriptomic Insights and Quantification of Free Amino Acids in Auricularia heimuer Cultivated on Corncob Substrate

open access: yesHorticulturae
Substrate type exerts a critical influence on the growth, development, and nutritional quality of Auricularia heimuer. In this study, agricultural waste-derived corncob was used as the treatment group (T1), with sawdust serving as the control (CK), to ...
Xu Sun   +8 more
doaj   +1 more source

miRNA-GABA influences female Aedes aegypti reproduction by modulating midgut homeostasis

open access: yesCell Reports
Summary: Aedes aegypti’s exceptional reproductive capacity drives the global proliferation of vector-borne diseases, including dengue, Zika, and chikungunya, while its hematophagous digestion supplies essential energy to catalyze critical reproductive ...
Jianping Cao, Lin Ling
doaj   +1 more source

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