Results 31 to 40 of about 30,715 (166)

Is there a correlation between GAD2 gene-243 A>G polymorphism and obesity?

Romanian Journal of Laboratory Medicine, 2019
Introduction: GAD2 gene encodes the glutamate decarboxylase enzyme which catalyses the transformation of glutamate into γ-aminobutyric acid, GABA.
Alkhzouz Camelia, Miclea Diana, Farcas Marius, Bucerzan Simona, Cabau Georgiana, Popp Radu Anghel   +5 more
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GABA and Glutamate Imbalance in Autism and Their Reversal as Novel Hypothesis for Effective Treatment Strategy

Аутизм и нарушение развития, 2020
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by reduced social communication and repetitive behaviors.
A. El-Ansary
doaj   +1 more source

Remission of diabetes with glutamic acid decarboxylase antibody positivity that developed after the administration of olanzapine: a case report [PDF]

Precision and Future Medicine
Olanzapine is a second-generation antipsychotic drug associated with the development of type 2 diabetes. However, the development and remission of diabetes with glutamic acid decarboxylase (GAD) antibody (Ab) positivity related to olanzapine treatment ...
Kyuho Kim, Soo Hyun Seo, Yun Ji Hong, Woojae Myung, Bomi Kim, Chang Ho Ahn, Sung Hee Choi, Hak Chul Jang, Tae Jung Oh   +8 more
doaj   +1 more source

Response of regional brain glutamate transaminases of rat to aluminum in protein malnutrition

BMC Neuroscience, 2002
Background The mechanism of aluminum-induced neurotoxicity is not clear. The involvement of glutamate in the aluminium-induced neurocomplications has been suggested. Brain glutamate levels also found to be altered in protein malnutrition.
Chatterjee Ajay K, Nayak Prasunpriya
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Ketogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy

Cell Discovery
Ketogenic diet (KD) alleviates refractory epilepsy and reduces seizures in children. However, the metabolic/cell biologic mechanisms by which the KD exerts its antiepileptic efficacy remain elusive.
Ya-Nan Qiao, Lei Li, Song-Hua Hu, Yuan-Xin Yang, Zhen-Zhen Ma, Lin Huang, Yan-Peng An, Yi-Yuan Yuan, Yan Lin, Wei Xu, Yao Li, Peng-Cheng Lin, Jing Cao, Jian-Yuan Zhao, Shi-Min Zhao   +14 more
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Preclinical type 1 diabetes mellitus: a case from practice

Лечащий Врач, 2021
At the preclinical stage diabetes mellitus can be diagnosed based on laboratory studies of blood glucose and detection of autoantibodies to insulin (IAA), islet cells (ICA), glutamate decarboxylase (GADA), tyrosine phosphatase (IA2A) and zinc transporter
Yu. G. Samoilova, T. A. Filippova, M. V. Koshmeleva, O. A. Oleynik, E. V. Gorbatenko   +4 more
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A plasmid-borne gadRCB operon contributes to acid tolerance in Lactiplantibacillus plantarum ZR79

Applied Microbiology and Biotechnology
The glutamate decarboxylase (GAD) system catalyzed the conversion of L-glutamate to gamma-aminobutyric acid (GABA) in a proton-consuming reaction, which played a critical role to maintain intracellular pH homeostasis.
Chengfei Fan, Zeyu Cao, Xinfeng Liu, Yan Hao, Zhengyuan Zhai, Yanling Hao   +5 more
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Comprehensive characterization of γ-aminobutyric acid (GABA) production by Levilactobacillus brevis CRL 2013: insights from physiology, genomics, and proteomics

Frontiers in Microbiology
IntroductionLevilactobacillus brevis CRL 2013, a plant-derived lactic acid bacterium (LAB) with immunomodulatory properties, has emerged as an efficient producer of γ-aminobutyric acid (GABA).
Pablo G. Cataldo, María Paulina Urquiza Martínez, Julio Villena, Haruki Kitazawa, Haruki Kitazawa, Lucila Saavedra, Elvira M. Hebert   +6 more
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The components required for amino acid neurotransmitter signaling are present in adipose tissues

Journal of Lipid Research, 2007
The adipocyte does not only serve as fuel storage but produces and secretes compounds with modulating effects on food intake and energy homeostasis.
Anne Nicolaysen, Runhild Gammelsaeter, Jon Storm-Mathisen, Vidar Gundersen, Per Ole Iversen   +4 more
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Partial Cloning and Nucleotide Sequencing of Glutamate Decarboxylase Gene Isoform 65 from Human Brain

Research in Molecular Medicine, 2015
Background: Gamma -aminobutyric acid (GABA), a non-protein amino acid acts as an inhibitory neurotransmitter in the central nervous system of mammalians. The glutamate decarboxylase (GAD) is responsible for the conversion of L-glutamate to GABA.
Abolghasem Esmaeili, Maliheh Dehghan
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