Results 31 to 40 of about 56,211 (247)

The Role of Elastase Antibodies, Circulating Autoantibodies to Glutamate Decarboxylase and Islet Cells Antigens in Chronic Pancreatitis

Gastroenterologìa, 2014
The article presents an analysis of the occurrence of elastase antibodies, circulating autoantibodies to glutamate decarboxylase and islet cells antigens in different forms of chronic pancreatitis.
V.Yu. Koval
doaj   +1 more source

Evidence for a GABAergic system in rodent and human testis: Local GABA production and GABA receptors [PDF]

, 2003
The major neurotransmitter of the central nervous system, gamma-aminobutyric acid (GABA), exerts its actions through GABA(A), GABA(B) and GABA(C) receptors.
Calandra, Ricardo S., Doepner, Richard F. G., Frungieri, Monica B., Gamel-Didelon, Katia, Geigerseder, Christof, Kohn, Frank M., Mayerhofer, Artur, Thalhammer, Andrea   +7 more
core   +2 more sources

Transaminations catalysed by brain glutamate decarboxylase [PDF]

Biochemical Journal, 1985
In addition to normal decarboxylation of glutamate to 4-aminobutyrate, glutamate decarboxylase from pig brain was shown to catalyse decarboxylation-dependent transamination of L-glutamate and direct transamination of 4-aminobutyrate with pyridoxal 5′-phosphate to yield succinic semialdehyde and pyridoxamine 5′-phosphate in a 1:1 stoichiometric ratio ...
T G, Porter, D C, Spink, S B, Martin, D L, Martin   +3 more
openaire   +2 more sources

Extraction and Quantification of GABA and Glutamate from Cyanobacterium Synechocystis sp. PCC 6803

Bio-Protocol, 2016
GABA (γ-amino butyric acid) is a biologically active four carbon non-protein amino acid found in prokaryotes and eukaryotes. Glutamate is a five carbon α-amino acid which can be converted to GABA catalyzed by the enzyme glutamate decarboxylase.
Simab Kanwal, Aran Incharoensakdi
doaj   +1 more source

The effect of sodium thiopental as a GABA mimetic drug in neonatal period on expression of GAD65 and GAD67 genes in hippocampus of newborn and adult male rats [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Objective(s): Development of the nervous system in human and most animals is continued after the birth. Critical role of this period in generation and specialization of the neuronal circuits is confirmed in numerous studies.
Masoud Naseri, Abbas Parham, Ali Moghimi
doaj   +1 more source

Gad65 is recognized by t-cells, but not by antibodies from nod-mice [PDF]

, 1994
Since the 64kDa-protein glutamic acid decarboxylase (GAD) is one of the major autoantigens in T-cell mediated Type 1 diabetes, its relevance as a T-cell antigen needs to be clarified. After isolation of splenic T-cells from non-obese diabetic (NOD) mice,
Alzari PM, Atkinson MA, Baekkeskov S, Bieg S, Christgau S, Christie MR, Diaz JL, Eisenbarth GS, Hackett CJ, Honeyman MC, J. Seissler, Jennings PA, L. Herberg, Leiter EH, Lie W, Mauch L, Miller LP, Ohneda A, Peters PJ, Roep BO, Roep BO, S. Bieg, Seissler J, Seissler J, Solimena M, Solimena M, Velloso LA, W. A. Scherbaum, W. Northemann   +28 more
core   +1 more source

Elevated histone H3 acetylation is associated with genes involved in T lymphocyte activation and glutamate decarboxylase antibody production in patients with type 1 diabetes

Journal of Diabetes Investigation, 2019
Aims/Introduction Genetic and epigenetic mechanisms have been implicated in the pathogenesis of type 1 diabetes, and histone acetylation is an epigenetic modification pattern that activates gene transcription.
Yanfei Wang, Can Hou, Jonathan Wisler, Kanhaiya Singh, Chao Wu, Zhiguo Xie, Qianjin Lu, Zhiguang Zhou   +7 more
doaj   +1 more source

Modulation of gene expression in guinea pig paraflocculus after induction of hearing loss [v2; ref status: indexed, http://f1000r.es/3c5]

F1000Research, 2014
Hearing loss often results in plastic changes in the central auditory pathways, which may be involved in the generation of tinnitus, a phantom auditory sensation.
Wilhelmina H. A. M. Mulders, Jennifer Rodger, Clarissa G. Yates, Donald Robertson   +3 more
doaj   +1 more source

Enhance Production of γ-Aminobutyric Acid (GABA) and Improve the Function of Fermented Quinoa by Cold Stress

Foods, 2022
Quinoa is an excellent source of γ-aminobutyric acid (GABA), which is a natural four-carbon non-protein amino acid with great health benefits. In this study, the quinoa was treated by cold stress before fermentation with Lactobacillus plantarum to ...
Yucui Zhang, Ming Zhang, Ting Li, Xinxia Zhang, Li Wang   +4 more
doaj   +1 more source

Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]

, 2006
The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core   +1 more source