Results 1 to 10 of about 574,846 (354)
Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons. [PDF]
Nat Commun, 2021 Tet3 is the main α-ketoglutarate (αKG)-dependent dioxygenase in neurons that converts 5-methyl-dC into 5-hydroxymethyl-dC and further on to 5-formyl- and 5-carboxy-dC.
Traube FR +17 more
europepmc +2 more sources
Isoenzymes of Glutamate Dehydrogenase in Plants [PDF]
Plant Physiology, 1969 Glutamate dehydrogenase of several different plants was resolved by polyacrylamide gel electrophoresis into separate molecular forms and the isoenzymic patterns detected by the tetrazolium technique were compared. The number of isoenzymes and their electrophoretic mobilities varied among the different plants studied.
Shuang Yue
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Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development [PDF]
Malaria Journal, 2011 <p>Background: Plasmodium falciparum contains three genes encoding potential glutamate dehydrogenases. The protein encoded by gdha has previously been biochemically and structurally characterized.
Aparicio, I. +7 more
core +5 more sources
A glutamate dehydrogenase gene sequence [PDF]
Nucleic Acids Research, 1989 A Chlorella sorokiniana genomic DNA library was screened with a NADP-specific glutamate dehydrogenase (GDH) cDNA. Two putative GDH sequences were isolated. One sequence is typically eukaryotic in that its coding region is interrupted by many introns (1). Southern blots showed that C.
Cock, J. Mark, Schmidt, Robert
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Glutamate Dehydrogenase Measurement
Definitions, 2020 The determination of the amount of glutamate dehydrogenase present in a sample.
semanticscholar +1 more source
npj Biofilms and Microbiomes, 2019 There are two glutamate dehydrogenases in the pathogenic fungus Candida albicans. One is an NAD+-dependent glutamate dehydrogenase (GDH2) and the other is an NADPH-dependent glutamate dehydrogenase (GDH3).
Ting-Li Han +3 more
semanticscholar +1 more source
Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency) [PDF]
, 2010 Pyridoxine-dependent epilepsy was recently shown to be due to mutations in the ALDH7A1 gene, which encodes antiquitin, an enzyme that catalyses the nicotinamide adenine dinucleotide-dependent dehydrogenation of L-{alpha}-aminoadipic semialdehyde/L-{Delta}
Adam +50 more
core +12 more sources
Glutamate Dehydrogenase to the Rescue [PDF]
Molecular Cell, 2018 Tumor cell metabolism can be altered to support specific pathological functions or to adapt to environmental stresses. In this issue of Molecular Cell, Jin et al. (2018) identify induction of glutamate dehydrogenase as a critical metabolic adaptation in matrix-detached cancer cells that is required for metastasis of LKB1-deficient lung tumors.
openaire +3 more sources
Studies of Glutamate Dehydrogenase [PDF]
European Journal of Biochemistry, 1974 The binding of NADH and NADPH to beef liver glutamate dehydrogenase has been investigated using fluorescence titration and the preparative as well as the analytical ultracentrifuge over a wide range of protein and coenzyme concentrations. The glutamate dehydrogenase oligomer (molecular weight 336000, six polypeptide chains) binds independent of enzyme ...
Horst Sund +2 more
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Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations [PDF]
, 2009 Background: Activating mutations in the GLUD1 gene (which encodes for the intra-mitochondrial enzyme glutamate dehydrogenase, GDH) cause the hyperinsulinism–hyperammonaemia (HI/HA) syndrome.
Banerjee, I. +9 more
core +2 more sources