A comparative analysis of fruit fly and human glutamate dehydrogenases in Drosophila melanogaster sperm development [PDF]
Frontiers in Cell and Developmental Biology, 2023 Glutamate dehydrogenases are enzymes that take part in both amino acid and energy metabolism. Their role is clear in many biological processes, from neuronal function to cancer development. The putative testis-specific Drosophila glutamate dehydrogenase,
Viktor Vedelek +6 more
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Integration of Glutamate Dehydrogenase and Nanoporous Gold for Electrochemical Detection of Glutamate [PDF]
Biosensors, 2023 Glutamate, a non-essential amino acid produced by fermentation, plays a significant role in disease diagnosis and food safety. It is important to enable the real-time monitoring of glutamate concentration for human health and nutrition.
Ting Cai +5 more
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Glutamate dehydrogenase hyperinsulinism: mechanisms, diagnosis, and treatment [PDF]
Orphanet Journal of Rare Diseases, 2023 Congenital hyperinsulinism (CHI) is a genetically heterogeneous disease, in which intractable, persistent hypoglycemia is induced by excessive insulin secretion and increased serum insulin concentration.
Qiao Zeng, Yan-Mei Sang
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Isoenzymes of Glutamate Dehydrogenase in Plants [PDF]
Plant Physiology, 1969 Glutamate dehydrogenase of several different plants was resolved by polyacrylamide gel electrophoresis into separate molecular forms and the isoenzymic patterns detected by the tetrazolium technique were compared. The number of isoenzymes and their electrophoretic mobilities varied among the different plants studied.
Shuang Yue
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Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons [PDF]
Nature Communications, 2021 α-ketoglutarate (αKG) is an intermediate in the tricarboxylic acid cycle that is required in the nucleus for genomic DNA demethylation by Tet3. Here, the authors show that the enzyme glutamate dehydrogenase, which converts glutamate to αKG, is redirected
Franziska R. Traube +17 more
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Physiological Role of Glutamate Dehydrogenase in Cancer Cells [PDF]
Frontiers in Oncology, 2020 NH4+ increased growth rates and final densities of several human metastatic cancer cells. To assess whether glutamate dehydrogenase (GDH) in cancer cells may catalyze the reverse reaction of NH4+ fixation, its covalent regulation and kinetic parameters ...
Rafael Moreno-Sánchez +7 more
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A glutamate dehydrogenase gene sequence [PDF]
Nucleic Acids Research, 1989 A Chlorella sorokiniana genomic DNA library was screened with a NADP-specific glutamate dehydrogenase (GDH) cDNA. Two putative GDH sequences were isolated. One sequence is typically eukaryotic in that its coding region is interrupted by many introns (1). Southern blots showed that C.
Cock, J. Mark, Schmidt, Robert
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CALCIUM AND MAGNESIUM CATIONS INFLUENCE ON ANTIMICROBIAL AND ANTIADHESIVE ACTIVITY OF ACINETOBACTER CALCOACETICUS ІMV B-7241 SURFACTANTS [PDF]
Biotechnologia Acta, 2016 The aim of the work was to study the effect of calcium and magnesium cations on NADP+-dependent glutamate dehydrogenase activity (key enzyme of biosynthesis of Acinetobacter calcoaceticus ІMV B-7241 surface-active aminolipids) followed by modification of
P. Pirog, I. V. Sidor, D. A. Lutsai
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Mitochondrial disorders in neuromuscular pathology
Нервно-мышечные болезни, 2019 Introduction. With the advent of new drugs — analogues of mitochondrial metabolites, the widespread introduction into practice of research methods for assessing the function of mitochondria in patients with neurological pathology and other diseases ...
S. V. Kotov +2 more
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Physiological regulation of isocitrate dehydrogenase and the role of 2-oxoglutarate in Prochlorococcus sp. strain PCC 9511. [PDF]
PLoS ONE, 2014 The enzyme isocitrate dehydrogenase (ICDH; EC 1.1.1.42) catalyzes the oxidative decarboxylation of isocitrate, to produce 2-oxoglutarate. The incompleteness of the tricarboxylic acids cycle in marine cyanobacteria confers a special importance to ...
María Agustina Domínguez-Martín +5 more
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