Results 11 to 20 of about 158,395 (286)

Integration of Glutamate Dehydrogenase and Nanoporous Gold for Electrochemical Detection of Glutamate. [PDF]

Biosensors (Basel), 2023
Glutamate, a non-essential amino acid produced by fermentation, plays a significant role in disease diagnosis and food safety. It is important to enable the real-time monitoring of glutamate concentration for human health and nutrition.
Cai T, Shang K, Wang X, Qi X, Liu R, Wang X.   +5 more
europepmc   +2 more sources

Glutamate dehydrogenase hyperinsulinism: mechanisms, diagnosis, and treatment. [PDF]

Orphanet J Rare Dis, 2023
Congenital hyperinsulinism (CHI) is a genetically heterogeneous disease, in which intractable, persistent hypoglycemia is induced by excessive insulin secretion and increased serum insulin concentration.
Zeng Q, Sang YM.
europepmc   +2 more sources

Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons. [PDF]

Nat Commun, 2021
α-ketoglutarate (αKG) is an intermediate in the tricarboxylic acid cycle that is required in the nucleus for genomic DNA demethylation by Tet3. Here, the authors show that the enzyme glutamate dehydrogenase, which converts glutamate to αKG, is redirected
Traube FR, Özdemir D, Sahin H, Scheel C, Glück AF, Geserich AS, Oganesian S, Kostidis S, Iwan K, Rahimoff R, Giorgio G, Müller M, Spada F, Biel M, Cox J, Giera M, Michalakis S, Carell T.   +17 more
europepmc   +2 more sources

Can Macromolecular Crowding Help Regulate Glutamate Dehydrogenase Activity? [PDF]

ACS Omega
Rosario G, Desrochers A, Robitaille A, Rundlett E, Myšák D, Sochorová Vokáčová Z, Timr Š, Pluhařová E, Slade KM.   +8 more
europepmc   +2 more sources

A comparative analysis of fruit fly and human glutamate dehydrogenases in Drosophila melanogaster sperm development

Frontiers in Cell and Developmental Biology, 2023
Glutamate dehydrogenases are enzymes that take part in both amino acid and energy metabolism. Their role is clear in many biological processes, from neuronal function to cancer development. The putative testis-specific Drosophila glutamate dehydrogenase,
Viktor Vedelek, Balázs Vedelek, Balázs Vedelek, Péter Lőrincz, Gábor Juhász, Gábor Juhász, Rita Sinka   +6 more
doaj   +1 more source

Sodium butyrate reduces ammonia emissions through glutamate metabolic pathways in cecal microorganisms of laying hens

Ecotoxicology and Environmental Safety, 2022
Ammonia emission is an important problem that needs to be solved in laying hen industries. Sodium butyrate (SB) is considered to have potential for reducing ammonia production because of its ability to improve nitrogen metabolism.
Zhikang Zhong, Chao Wang, Huaidan Zhang, Jiandui Mi, Juan Boo Liang, Xindi Liao, Yinbao Wu, Yan Wang   +7 more
doaj   +1 more source

CALCIUM AND MAGNESIUM CATIONS INFLUENCE ON ANTIMICROBIAL AND ANTIADHESIVE ACTIVITY OF ACINETOBACTER CALCOACETICUS ІMV B-7241 SURFACTANTS [PDF]

Biotechnologia Acta, 2016
The aim of the work was to study the effect of calcium and magnesium cations on NADP+-dependent glutamate dehydrogenase activity (key enzyme of biosynthesis of Acinetobacter calcoaceticus ІMV B-7241 surface-active aminolipids) followed by modification of
P. Pirog, I. V. Sidor, D. A. Lutsai
doaj   +1 more source

The role of glutamate dehydrogenase in the ageing brain. [PDF]

Front Pharmacol
The homeostasis of glutamate, the primary excitatory neurotransmitter in the brain and is crucial for normal brain function. The mitochondrial enzyme glutamate dehydrogenase (GDH) connects the multifunctional amino acid glutamate, which is intimately ...
Zhou T, Wang H.
europepmc   +2 more sources

Mitochondrial disorders in neuromuscular pathology

Нервно-мышечные болезни, 2019
Introduction. With the advent of new drugs — analogues of mitochondrial metabolites, the widespread introduction into practice of research methods for assessing the function of mitochondria in patients with neurological pathology and other diseases ...
S. V. Kotov, O. P. Sidorova, E. V. Borodataya   +2 more
doaj   +1 more source

The dnaJ (hsp40) Locus in Rhizobium leguminosarum bv. phaseoli Is Required for the Establishment of an Effective Symbiosis with Phaseolus vulgaris

Molecular Plant-Microbe Interactions, 2000
P121R25 is a Tn5-induced mutant of the effective Rhizobium leguminosarum bv. phaseoli strain P121R that is unable to use glutamate as the sole carbon and nitrogen source and is defective in symbiotic nitrogen fixation.
Mohamed Labidi, Serge Laberge, Louis P. Vézina, Hani Antoun   +3 more
doaj   +1 more source