Results 11 to 20 of about 157,588 (333)

Integration of Glutamate Dehydrogenase and Nanoporous Gold for Electrochemical Detection of Glutamate [PDF]

open access: yesBiosensors, 2023
Glutamate, a non-essential amino acid produced by fermentation, plays a significant role in disease diagnosis and food safety. It is important to enable the real-time monitoring of glutamate concentration for human health and nutrition.
Ting Cai   +5 more
doaj   +2 more sources

Glutamate dehydrogenase hyperinsulinism: mechanisms, diagnosis, and treatment [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2023
Congenital hyperinsulinism (CHI) is a genetically heterogeneous disease, in which intractable, persistent hypoglycemia is induced by excessive insulin secretion and increased serum insulin concentration.
Qiao Zeng, Yan-Mei Sang
doaj   +2 more sources

Isoenzymes of Glutamate Dehydrogenase in Plants [PDF]

open access: greenPlant Physiology, 1969
Glutamate dehydrogenase of several different plants was resolved by polyacrylamide gel electrophoresis into separate molecular forms and the isoenzymic patterns detected by the tetrazolium technique were compared. The number of isoenzymes and their electrophoretic mobilities varied among the different plants studied.
Shuang Yue
openalex   +4 more sources

Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons [PDF]

open access: yesNature Communications, 2021
α-ketoglutarate (αKG) is an intermediate in the tricarboxylic acid cycle that is required in the nucleus for genomic DNA demethylation by Tet3. Here, the authors show that the enzyme glutamate dehydrogenase, which converts glutamate to αKG, is redirected
Franziska R. Traube   +17 more
doaj   +2 more sources

The role of glutamate dehydrogenase in the ageing brain [PDF]

open access: yesFrontiers in Pharmacology
The homeostasis of glutamate, the primary excitatory neurotransmitter in the brain and is crucial for normal brain function. The mitochondrial enzyme glutamate dehydrogenase (GDH) connects the multifunctional amino acid glutamate, which is intimately ...
Tao Zhou, Haichuan Wang
doaj   +2 more sources

Physiological Role of Glutamate Dehydrogenase in Cancer Cells [PDF]

open access: yesFrontiers in Oncology, 2020
NH4+ increased growth rates and final densities of several human metastatic cancer cells. To assess whether glutamate dehydrogenase (GDH) in cancer cells may catalyze the reverse reaction of NH4+ fixation, its covalent regulation and kinetic parameters ...
Rafael Moreno-Sánchez   +7 more
doaj   +2 more sources

A comparative analysis of fruit fly and human glutamate dehydrogenases in Drosophila melanogaster sperm development

open access: yesFrontiers in Cell and Developmental Biology, 2023
Glutamate dehydrogenases are enzymes that take part in both amino acid and energy metabolism. Their role is clear in many biological processes, from neuronal function to cancer development. The putative testis-specific Drosophila glutamate dehydrogenase,
Viktor Vedelek   +6 more
doaj   +1 more source

Sodium butyrate reduces ammonia emissions through glutamate metabolic pathways in cecal microorganisms of laying hens

open access: yesEcotoxicology and Environmental Safety, 2022
Ammonia emission is an important problem that needs to be solved in laying hen industries. Sodium butyrate (SB) is considered to have potential for reducing ammonia production because of its ability to improve nitrogen metabolism.
Zhikang Zhong   +7 more
doaj   +1 more source

A glutamate dehydrogenase gene sequence [PDF]

open access: yesNucleic Acids Research, 1989
A Chlorella sorokiniana genomic DNA library was screened with a NADP-specific glutamate dehydrogenase (GDH) cDNA. Two putative GDH sequences were isolated. One sequence is typically eukaryotic in that its coding region is interrupted by many introns (1). Southern blots showed that C.
Cock, J. Mark, Schmidt, Robert
openaire   +4 more sources

CALCIUM AND MAGNESIUM CATIONS INFLUENCE ON ANTIMICROBIAL AND ANTIADHESIVE ACTIVITY OF ACINETOBACTER CALCOACETICUS ІMV B-7241 SURFACTANTS [PDF]

open access: yesBiotechnologia Acta, 2016
The aim of the work was to study the effect of calcium and magnesium cations on NADP+-dependent glutamate dehydrogenase activity (key enzyme of biosynthesis of Acinetobacter calcoaceticus ІMV B-7241 surface-active aminolipids) followed by modification of
P. Pirog, I. V. Sidor, D. A. Lutsai
doaj   +1 more source

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