Results 11 to 20 of about 142,175 (352)

Studies of Glutamate Dehydrogenase [PDF]

open access: yesEuropean Journal of Biochemistry, 1974
The binding of NADH and NADPH to beef liver glutamate dehydrogenase has been investigated using fluorescence titration and the preparative as well as the analytical ultracentrifuge over a wide range of protein and coenzyme concentrations. The glutamate dehydrogenase oligomer (molecular weight 336000, six polypeptide chains) binds independent of enzyme ...
Horst Sund   +2 more
openaire   +3 more sources

The dnaJ (hsp40) Locus in Rhizobium leguminosarum bv. phaseoli Is Required for the Establishment of an Effective Symbiosis with Phaseolus vulgaris

open access: yesMolecular Plant-Microbe Interactions, 2000
P121R25 is a Tn5-induced mutant of the effective Rhizobium leguminosarum bv. phaseoli strain P121R that is unable to use glutamate as the sole carbon and nitrogen source and is defective in symbiotic nitrogen fixation.
Mohamed Labidi   +3 more
doaj   +1 more source

Biochemical and Enzymatic Analyses to Understand the Accumulation of γ-Aminobutyric Acid in Wheat Grown under Flooding Stress

open access: yesOxygen, 2023
Flooding induces low-oxygen stress, which reduces plant growth. The activity of the γ-aminobutyric acid (GABA) shunt is crucial for plant stress adaptation, in which it acts by changing cytosolic pH, limiting reactive oxygen species production ...
Setsuko Komatsu   +2 more
doaj   +1 more source

Physiological role and regulation of glutamate dehydrogenase in Prochlorococcus sp. strain MIT9313 [PDF]

open access: yes, 2009
Glutamate dehydrogenase is an enzyme catalysing a reaction for ammonium assimilation, alternative to those performed by glutamine synthetase and glutamate synthase.
Diez, Jesús   +4 more
core   +1 more source

Glutamate Dehydrogenase to the Rescue [PDF]

open access: yesMolecular Cell, 2018
Tumor cell metabolism can be altered to support specific pathological functions or to adapt to environmental stresses. In this issue of Molecular Cell, Jin et al. (2018) identify induction of glutamate dehydrogenase as a critical metabolic adaptation in matrix-detached cancer cells that is required for metastasis of LKB1-deficient lung tumors.
openaire   +3 more sources

Critical appraisal on mitochondrial dysfunction in Alzheimer’s disease

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 272-280, December 2022., 2022
Amyloid plaques deposit on neurons in case of Alzheimer's Disease. Mitochondria play a vital role in pathogenesis of Alzheimer's Disease. Mitochondrial dysfunction can lead to formation of mPTP, alteration of complexes 1,3 and 4, deficits in bioenergetics with impaired mitochondrial biogenesis. Abstract It is widely recognized that Alzheimer's disease (
Faizan Ahmad, Punya Sachdeva
wiley   +1 more source

The impact of RNA binding proteins and the associated long non-coding RNAs in the TCA cycle on cancer pathogenesis

open access: yesRNA Biology, 2023
The tricarboxylic acid (TCA) cycle is a central route for generating cellular energy and precursors for biosynthetic pathways. Emerging evidences have shown that the aberrations of metabolic enzymes which affect the integrity of TCA cycle are implicated ...
Tao Shen   +4 more
doaj   +1 more source

Molecular mechanisms of the non-coenzyme action of thiamin in brain. Biochemical, structural and pathway analysis [PDF]

open access: yes, 2015
Thiamin (vitamin B1) is a pharmacological agent boosting central metabolism through the action of the coenzyme thiamin diphosphate (ThDP). However, positive effects, including improved cognition, of high thiamin doses in neurodegeneration may be ...
Andrey, Vovk   +9 more
core   +1 more source

A thermophilic microorganism from Deception Island, Antarctica with a thermostable glutamate dehydrogenase activity

open access: yesBiological Research, 2018
Background The Antarctic continent is a source of extreme microorganisms. Millions of years of isolation have produced unique biodiversity with adaptive responses to its extreme environment.
Patricio A. M. Flores   +2 more
doaj   +1 more source

Theoretical Analysis of the Built-in Metabolic Pathway Effect on the Metabolism of Erythrocyte-Bioreactors That Neutralize Ammonium

open access: yesMetabolites, 2021
The limitations of the efficiency of ammonium-neutralizing erythrocyte-bioreactors based on glutamate dehydrogenase and alanine aminotransferase reactions were analyzed using a mathematical model.
Evgeniy Protasov   +4 more
doaj   +1 more source

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