Results 231 to 240 of about 157,588 (333)

Peri‐ and Postnatal High Fat Feeding Have Differential Effects on Executive Function and Associated Neurobiology in Aged Male and Female Mice

open access: yesAging Cell, EarlyView.
Postnatal high fat (HF) feeding negatively impacts executive function in both adult and aged mice, but consumption of the same diet during the perinatal period only is beneficial in older age. Maternal HF diet is associated with increased cholinergic innervation of the prefrontal cortex of young, but not aged, offspring.
Laura Contu   +3 more
wiley   +1 more source

Enhancing Late‐Life Survival and Mobility via Mitohormesis by Reducing Mitochondrial Calcium Levels

open access: yesAging Cell, EarlyView.
RNAi knockdown (KD) of mcu‐1 or mitoxantrone treatment lowers mitochondrial Ca2+, extends lifespan, and preserves motility during aging. Benefits require early intervention and involve a transient ROS increase that activates a pmk‐1, daf‐16, and skn‐1 pathway, enhancing stress defense and mitochondrial integrity while reducing early‐life survival ...
Doruntina Bresilla   +13 more
wiley   +1 more source

Bovine Liver Glutamate Dehydrogenase

open access: hybrid, 1970
Dennis Piszkiewicz   +2 more
openalex   +1 more source

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