Results 41 to 50 of about 574,846 (354)
Giardia duodenalis is a small intestinal protozoan parasite of several terrestrial vertebrates. This work aims to assess the genotypic variability of Giardia duodenalis isolates from cattle, sheep and pigs in the Southeast of Brazil, by comparing the ...
N. Fava+9 more
semanticscholar +1 more source
An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon+5 more
wiley +1 more source
Studies of Glutamate Dehydrogenase [PDF]
The investigation of the association‐dissociation equilibrium of beef liver glutamate dehydrogenase by light‐scattering measurements over a wide range of protein concentration (0.02 to 50 mg/ml) has shown that this equilibrium can be described as an open equilibrium (Mi+n Mh⇋ Mi+h, i and h≥ 1, M = oligomer) with identical equilibrium constants for all ...
Klaus Markau, Jens Schneider, Horst Sund
openaire +3 more sources
Inhibitors of Glutamate Dehydrogenase Block Sodium-Dependent Glutamate Uptake in Rat Brain Membranes
We recently found evidence for anatomic and physical linkages between the astroglial Na+-dependent glutamate transporters (GLT-1/EAAT2 and GLAST/EAAT1) and mitochondria.
Brendan S. Whitelaw, M. Robinson
semanticscholar +1 more source
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian+15 more
wiley +1 more source
FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang+14 more
wiley +1 more source
Metabolism of amino acid amides in Pseudomonas putida ATCC 12633 [PDF]
The metabolism of the natural amino acid L-valine, the unnatural amino acids D-valine, and D-, L-phenylglycine (D-, L-PG), and the unnatural amino acid amides D-, L-phenylglycine amide (D, L-PG-NH2) and L-valine amide (L-Val-NH2) was studied in ...
Croes, L.M.,+4 more
core +1 more source
Glutamate dehydrogenase contributes to leucine sensing in the regulation of autophagy
Amino acids, leucine in particular, are known to inhibit autophagy, at least in part by their ability to stimulate MTOR-mediated signaling. Evidence is presented showing that glutamate dehydrogenase, the central enzyme in amino acid catabolism ...
S. Lorin+7 more
semanticscholar +1 more source
In vivo SALI therapy is achieved by scavenging intracellular ROS levels, downregulating inflammatory factors expression levels, inducing macrophage M2 directional polarization, and activating Keap1/Nrf‐2/HO‐1 pathway to reprogram redox homeostasis, induce cellular autophagy, reduce systemic inflammation, and promote liver tissue repair. Abstract Sepsis
Tao Qin+21 more
wiley +1 more source
Serine biosynthesis with one carbon catabolism represents a novel pathway for ATP generation in cells using alternative glycolysis with zero net ATP production [PDF]
Recent experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP.
Alexei Vazquez+2 more
core +2 more sources