Results 41 to 50 of about 142,175 (352)
The role of glutamine oxoglutarate aminotransferase and glutamate dehydrogenase in nitrogen metabolism in Mycobacterium bovis BCG. [PDF]
PLoS ONE, 2013 Recent evidence suggests that the regulation of intracellular glutamate levels could play an important role in the ability of pathogenic slow-growing mycobacteria to grow in vivo.
Albertus J Viljoen +4 more
doaj +1 more source
Bonded Cumomer Analysis of Human Melanoma Metabolism Monitored by 13C NMR Spectroscopy of Perfused Tumor Cells. [PDF]
, 2015 A network model for the determination of tumor metabolic fluxes from (13)C NMR kinetic isotopomer data has been developed and validated with perfused human DB-1 melanoma cells carrying the BRAF V600E mutation, which promotes oxidative metabolism.
Blair, Ian A +9 more
core +2 more sources
Retinal regions shape human and murine Müller cell proteome profile and functionality
Glia, Volume 71, Issue 2, Page 391-414, February 2023., 2023 Main Points We defined Müller cells heterogeneity in the macular and peripheral human retina. Signaling pathways shaping this glial heterogeneity include proteins important for interaction with vesicular secretion, extracellular matrix and cell adhesion.
Lew Kaplan +15 more
wiley +1 more source
Integrating gene and protein expression data with genome-scale metabolic networks to infer functional pathways [PDF]
, 2013 This article has been made available through the Brunel Open Access Publishing Fund. Copyright @ 2013 Pey et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://
Beasley, JE +4 more
core +1 more source
The intracellular location of nitrogen metabolism enzymes in Pisum arvense L. roots
Acta Societatis Botanicorum Poloniae, 2014 The time course changes of nitrate assimilation enzymes and their distribution has been studied in Pisum arvense roots. The results indicate that nitrate reductase (EC 1.6.6.2) and glutamine synthetase (EC 6.3.1.2) are present in the soluble fraction ...
Grażyna Kłobus +2 more
doaj +1 more source
Glutamate biosynthesis in Bacillus azotofixans. 15N NMR and enzymatic studies [PDF]
, 1988 Pathways of ammonia assimilation into glutamic acid in Bacillus azotofixans, a recently characterized nitrogen-fixing species of Bacillus, were investigated through observation by NMR spectroscopy of in vivo incorporation of 15N into glutamine and ...
Kanamori, Keiko +2 more
core
Metabolic plasticity of tumor cell mitochondria [PDF]
, 2018 open5noMitochondria are dynamic organelles that exchange a multiplicity of signals with other cell compartments, in order to finely adjust key biological routines to the fluctuating metabolic needs of the cell.
core +1 more source
Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies [PDF]
, 1987 Pathways of ammonia assimilation into glutamic acid and alanine in Bacillus polymyxa were investigated by 15N NMR spectroscopy in combination with measurements of the specific activities of glutamate dehydrogenase, glutamine synthetase, glutamate ...
Kanamori, Keiko +2 more
core