Results 41 to 50 of about 572,195 (400)

Platelet glutamate dehydrogenase activity and efficacy of antipsychotic therapy in patients with schizophrenia [PDF]

Journal of Medical Biochemistry, 2020
Background: Evaluation of possible relationship between platelet glutamate dehydrogenase (GDH) activity and mental state of schizophrenia patients after antipsychotic pharmacotherapy. Methods: Patients (n = 50) with chronic paranoid schizophrenia (F20.0)
Savushkina Olga K., Tereshkina Elena B., Prokhorova Tatiana A., Boksha Irina S., Burminskii Denis S., Vorobyeva Elena A., Morozova Margarita A., Burbaeva Gulnur Sh.   +7 more
doaj  

METABOLIC PLATELET STATUS IN PATIENTS WITH STABLE ANGINA

Российский кардиологический журнал, 2013
Aim. To study the activity of NAD- and NADP-dependent platelet dehydrogenases in patients with various functional classes of angina. Material and methods. The study included 91 men with Functional Class II–IV angina, aged 45–72 years. In all participants,
I. Yu. Grinstein, A. A. Savchenko, E. A. Savchenko, A. A. Kosinova, Yu. I. Grinstein   +4 more
doaj   +1 more source

Cancer metabolism at a glance [PDF]

, 2016
A defining hallmark of cancer is uncontrolled cell proliferation. This is initiated once cells have accumulated alterations in signaling pathways that control metabolism and proliferation, wherein the metabolic alterations provide the energetic and ...
Gottlieb, Eyal, Kamphorst, Jurre J., Markert, Elke K., Schug, Zachary T., Tardito, Saverio, Vazquez, Alexei   +5 more
core   +2 more sources

Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain

Biomolecules, 2016
Glutamate is present in the brain at an average concentration—typically 10–12 mM—far in excess of those of other amino acids. In glutamate-containing vesicles in the brain, the concentration of glutamate may even exceed 100 mM. Yet because glutamate is a
Arthur J. L. Cooper, Thomas M. Jeitner
doaj   +1 more source

The role of glutamine oxoglutarate aminotransferase and glutamate dehydrogenase in nitrogen metabolism in Mycobacterium bovis BCG. [PDF]

PLoS ONE, 2013
Recent evidence suggests that the regulation of intracellular glutamate levels could play an important role in the ability of pathogenic slow-growing mycobacteria to grow in vivo.
Albertus J Viljoen, Catriona J Kirsten, Bienyameen Baker, Paul D van Helden, Ian J F Wiid   +4 more
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients

Journal of Translational Medicine, 2015
BackgroundGlutamate dehydrogenase (GDH) is a key enzyme that catalyzes the final reaction of the glutamine metabolic pathway, and has been reported implicated in tumor growth and metastasis.
Gaojie Liu, Jie Zhu, Menglei Yu, Canfeng Cai, Yu Zhou, Min Yu, Zhiqiang Fu, Yuanfeng Gong, Bin Yang, Ying-ru Li, Quanbo Zhou, Qing Lin, Huilin Ye, Liangtao Ye, Xiaohui Zhao, Zhihua Li, Rufu Chen, F. Han, Chaoming Tang, Bing Zeng   +19 more
semanticscholar   +1 more source

The intracellular location of nitrogen metabolism enzymes in Pisum arvense L. roots

Acta Societatis Botanicorum Poloniae, 2014
The time course changes of nitrate assimilation enzymes and their distribution has been studied in Pisum arvense roots. The results indicate that nitrate reductase (EC 1.6.6.2) and glutamine synthetase (EC 6.3.1.2) are present in the soluble fraction ...
Grażyna Kłobus, Genowefa Kłobus-Dobosz, Józef Buczek   +2 more
doaj   +1 more source

Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies [PDF]

, 1987
Pathways of ammonia assimilation into glutamic acid and alanine in Bacillus polymyxa were investigated by 15N NMR spectroscopy in combination with measurements of the specific activities of glutamate dehydrogenase, glutamine synthetase, glutamate ...
Kanamori, Keiko, Roberts, John D., Weiss, Richard L.   +2 more
core  

Determination of Glutamate Dehydrogenase Activity and Its Kinetics in Mouse Tissues using Metabolic Mapping (Quantitative Enzyme Histochemistry)

Journal of Histochemistry and Cytochemistry, 2014
Glutamate dehydrogenase (GDH) catalyses the reversible conversion of glutamate into α-ketoglutarate with the concomitant reduction of NAD(P)+ to NAD(P)H or vice versa.
D. Botman, W. Tigchelaar, C. van Noorden
semanticscholar   +1 more source