Results 151 to 160 of about 2,577,793 (359)

Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.

, 1991
Jae‐Young Koh, Elizabeth E. Palmer, CW Cotman   +2 more
openalex   +1 more source

The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells [PDF]

, 1990
Michael J. Courtney, JJ Lambert, D.G. Nicholls   +2 more
openalex   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Glutamate receptors induce a burst of superoxide via activation of nitric oxide synthase in arginine-depleted neurons.

, 1994
Marcel Culcasi, Mireille Lafon‐Cazal, Sylvia Pietri, Joël Bockaert   +3 more
openalex   +1 more source

Activation of metabotropic glutamate receptors increases cAMP accumulation in hippocampus by potentiating responses to endogenous adenosine [PDF]

, 1993
D G Winder, P. Jeffrey Conn
openalex   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex

Neurobiology of Disease, 2007
In addition to the loss of spinal motor neurons, amyotrophic lateral sclerosis (ALS) is also associated with degeneration of corticospinal layer V pyramidal neurons and decreased glutamate transport in the cortex. We characterized the glutamate receptors
Kate C. Young, Daniel S. McGehee, James R. Brorson   +2 more
doaj  

Gating kinetics of the quisqualate-sensitive glutamate receptor of locust muscle studied using agonist concentration jumps and computer simulations

, 1993
Claire J. Standley, Tyrrell Norris, R. L. Ramsey, P.N.R. Usherwood   +3 more
openalex   +1 more source

The striatal mosaic in primates: striosomes and matrix are differentially enriched in ionotropic glutamate receptor subunits [PDF]

, 1993
LJ Martin, CD Blackstone, RL Huganir, DL Price   +3 more
openalex   +1 more source

The role of glutamate and its receptors in autism and the use of glutamate receptor antagonists in treatment

Journal of neural transmission, 2014
D. Rojas
semanticscholar   +1 more source