Results 171 to 180 of about 2,577,793 (359)

Molecular evolution of glutamate receptors: a primitive signaling mechanism that existed before plants and animals diverged [PDF]

open access: bronze, 1999
Joanna C. Chiu   +4 more
openalex   +1 more source

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

open access: yesAdvanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding   +19 more
wiley   +1 more source

Polyploidy-mediated variations in glutamate receptor proteins linked to Fusarium wilt resistance in upland cotton. [PDF]

open access: yesPlant J
Parris S   +18 more
europepmc   +1 more source

Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley   +1 more source

Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1 [PDF]

open access: hybrid, 1995
C. Joly   +5 more
openalex   +1 more source

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches

open access: yesAdvanced Science, EarlyView.
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan   +10 more
wiley   +1 more source

Metabotropic Glutamate Receptor 5: A Potential Target for Neuropathic Pain Treatment. [PDF]

open access: yesCurr Neuropharmacol
Manengu C   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy