Results 151 to 160 of about 314,122 (297)

Sex differences in AMPA receptor trafficking proteins

Biology of Sex Differences
AMPA receptors are a type of ionotropic glutamate receptor that is important for fast excitatory neurotransmission. healthy brain function. Glutamate signaling is regulated, in part, by the trafficking of glutamate receptors in and out of the synapse ...
Mia Y. Roberts, Lisa A. Briand
doaj   +1 more source

m.10010T>C Mitochondrial Disease: A Case Report With Hypoparathyroidism and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mitochondria are essential intracellular organelles that play a critical role in cellular metabolism, including the regulation of intracellular calcium signaling. Advances in genomic sequencing have facilitated the identification of rare pathogenic mitochondrial DNA (mtDNA) genetic variants in patients with unexplained endocrine disorders.
Jacob Mohr, Anja Lisbeth Frederiksen, Morten Duno, Anne Pernille Hermann, Trine Maxel Juul, Simone Rask Nielsen   +5 more
wiley   +1 more source

Modeling the use of transient ligand binding information by AMPA receptors

npj Systems Biology and Applications
Glutamate mediates fast excitatory neurotransmission through α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors in the central nervous system.
Helena Braunstein, Alejandra C. Ventura, Alejandro Colman-Lerner   +2 more
doaj   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation

Angewandte Chemie, EarlyView.
The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner, Kai Rogge, Felix Trottmann, Christian Hertweck, Dirk Hoffmeister   +4 more
wiley   +2 more sources

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

Paradoxical Expression of Ionotropic Glutamate Receptors in Leucocytes. [PDF]

Clin Rev Allergy Immunol
Clanchy FIL, Williams RO, Stone TW.
europepmc   +1 more source

Endothelium glutamate receptors in brain pathology. [PDF]

Front Pharmacol
Pirozhkov SV, Vukolova MN, Bulgakova VV, Lutokhina YA, Bolevich SB, Sobolevsky AI, Yelshanskaya MV.   +6 more
europepmc   +1 more source

Polysialic Acid Modulation of Glutamate Receptors and Synaptic Mechanisms Underlying Neuronal Plasticity. [PDF]

NeuroSci
Chowdhury KU, Bhattacharya S, Uddin MR, Reed MN, Lee SG, Suppiramaniam V.   +5 more
europepmc   +1 more source

The role of ionotropic glutamate receptors in Alzheimer's disease: A scientometric analysis. [PDF]

J Alzheimers Dis
Liu Y, Zhong R, Li Q, Wang Y, Zhang J, Kou Z.   +5 more
europepmc   +1 more source