Results 131 to 140 of about 800,419 (299)
Glutamate receptors and schizophrenia [PDF]
Journal of Psychopharmacology, 1987 B S, Meldrum, R W, Kerwin
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Advanced Science, EarlyView.Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu +16 more
wiley +1 more source
, 1988 Muscle tension recordings were made from earthworm body wall muscle and the action of acetylcholine, cholinomimtics and cholinolytics examined. The effect of cholinergic agents on muscle twitches induced following field stimulation was also investigated.
Hassoni, Abdul-Nabi Atya, Hassoni, A.A
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Mecanismos de neuroproteção da guanosina contra a neurotoxicidade induzida por isquemia e dano oxidativo mitocondrial in vitro [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasA guanosina (GUO) é um modulador endógeno da excitotoxicidade glutamatérgica e promove neuroproteção em modelos de ...
Dal-Cim, Tharine Aparecida
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TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
Advanced Science, EarlyView.A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Comparative analyses of rodent and human brain in ageing and disease using novel NMDAR-2B selective probes [PDF]
, 2007 The NMDA subtype of excitatory ionotropic glutamate receptors is a hetero-oligomeric ligand-gated ion channel. Molecular cloning techniques have identified three types of NMDA receptor subunits, the NR 1, NR2A-D, and NR3A-B. NR2B-containing receptors are
Sheahan, Rebecca Louise
core
Advanced Science, EarlyView.Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang +4 more
wiley +1 more source
mGlu2 Receptors in the Basal Ganglia: A New Frontier in Addiction Therapy
Frontiers in Bioscience-LandmarkGlutamate is an important neurotransmitter in the mammalian brain. Among the receptors that glutamate interacts with is metabotropic glutamate (mGlu) receptor 2, a Gαi/o-coupled receptor.
Li-Min Mao +2 more
doaj +1 more source
Plasticity of GABAB receptor-mediated heterosynaptic interactions at mossy fibers after status epilepticus [PDF]
, 2003 Several neurotransmitters, including GABA acting at presynaptic GABAB receptors, modulate glutamate release at synapses between hippocampal mossy fibers and CA3 pyramidal neurons.
Bowery, N.G. +10 more
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Advanced Science, EarlyView.AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia +10 more
wiley +1 more source