Results 121 to 130 of about 65,396 (291)
Anatomy and Function of Ventral Tegmental Area Glutamate Neurons [PDF]
, 2022 Jing Cai, Qingchun Tong
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Advanced Science, EarlyView.Impulsivity is a symptom across multiple psychiatric disorders, yet its neural basis remains elusive. This study shows that the NMDAR antagonist MK‐801 elevates dopamine release and disrupts neuronal selectivity in the nucleus accumbens, leading to impulsive behavior.
Xueru Wang +6 more
wiley +1 more source
TRAP-seq identifies cystine/glutamate antiporter as a driver of recovery from liver injury
, 2018 Amber W. Wang +6 more
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Regulation of Glutamate, GABA and Dopamine Transporter Uptake, Surface Mobility and Expression [PDF]
, 2021 Renae M. Ryan +2 more
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Advanced Science, EarlyView.This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source
Trifluoperazine and dibucaine‐induced inhibition of glutamate‐induced mitochondrial depolarization in rat cultured forebrain neurones [PDF]
, 1997 Kari R. Hoyt +2 more
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Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Advanced Science, EarlyView.Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
Advanced Science, EarlyView.Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li +13 more
wiley +1 more source
Ripa-56 protects retinal ganglion cells in glutamate-induced retinal excitotoxic model of glaucoma [PDF]
Lemeng Feng +7 more
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Glutamate Cysteine Ligase—Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage [PDF]
, 2016 Suzie Lavoie +5 more
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