Results 141 to 150 of about 226,163 (382)
Cross-talks between Metabolic and Translational Controls during Beige Adipocyte Differentiation
Nature CommunicationsWhether and how regulatory events at the translation stage shape the cellular and metabolic features of thermogenic adipocytes is hardly understood.
Daehwa Youn +13 more
doaj +1 more source
Applied Food ResearchMonosodium glutamate (MSG), a flavor-enhancing substance, was re-evaluated by the European Food Safety Authority (EFSA) in 2017, which established an acceptable daily intake (ADI) of 0–30 mg/kg bw/day.
Weining Tian +15 more
doaj +1 more source
Structure and Electrochemical Properties of ReS2‐LaFeO3 Nanocomposite for Dopamine Sensing
Advanced Sensor Research, EarlyView.A novel ReS2‐LaFeO3 nanocomposite is developed for sensitive and reliable detection of dopamine (DA), an important neurotransmitter. The material performs well even in complex biological samples, demonstrating strong selectivity and accuracy. These findings highlight its potential for future applications in medical diagnostics and neuroscience research.
Obed Graham Keelson +5 more
wiley +1 more source
Cytokine Engineering Approaches for Regenerative Medicine
Advanced Therapeutics, EarlyView.Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley +1 more source
Compartmentation of glutamate metabolism in brain. Evidence for the existence of two different tricarboxylic acid cycles in brain [PDF]
, 1969 C. J. Van den Berg +3 more
openalex +1 more source
The role of glutamate in dementia
, 1998 Glutamate is an excitatory neurotransmitter, but may also act as an endogenous neurotoxin. There is good evidence for an involvement of the glutamatergic system in the pathophysiology of dementia. The glutamatergic transmission machinery is quite complex and provides a gallery of possible drug targets.
Kornhuber, J. +4 more
openaire +4 more sources
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Fact or Fiction? The MSG Controversy [PDF]
, 2012 Monosodium glutamate (“MSGâ€) has become one of the most well-known and controversial food ingredients in recent history. Linked to the “Chinese Restaurant Syndrome,†the use of MSG has caused ...
Singh, Monica
core
Advanced Theory and Simulations, EarlyView.Magnetoelectric nanoparticles exploit cancer cells' electrical vulnerabilities—altered membrane charge and higher capacitance—to achieve tumor‐specific targeting without bioreagents. MATLAB simulations reveal how electromagnetic forces create targeting specificity, while external magnetic fields enhance precision. This may enable wirelessly controlled,
Max Shotbolt +3 more
wiley +1 more source
LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing
Advanced Science, EarlyView.This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang +15 more
wiley +1 more source