Results 141 to 150 of about 66,132 (287)

Competition Between Liquid‐Liquid Crystalline Phase Separation (LLCPS) and Liquid‐Liquid Phase Separation (LLPS) in Amyloid Fibril Colloidal Systems

open access: yesAdvanced Science, EarlyView.
This study shows that amyloid fibrils form nematic condensates via liquid–liquid crystalline phase separation (LLCPS). With increasing pH, this transition shifts toward disordered condensates formed through liquid–liquid phase separation (LLPS), in which birefringence with lack of a coherent nematic field symmetry originates from enthalpic fibril ...
Milad Radiom, Raffaele Mezzenga
wiley   +1 more source

Electrostatic Ratchet for Successive Peptide Synthesis in Nonribosomal Molecular Machine RimK. [PDF]

open access: yesJ Am Chem Soc, 2023
Ohnuki J   +5 more
europepmc   +1 more source

Light-Activatable, 2,5-Disubstituted Tetrazoles for the Proteome-wide Profiling of Aspartates and Glutamates in Living Bacteria

open access: yesACS Central Science, 2020
Kathrin Bach   +3 more
doaj   +1 more source

Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative

open access: hybrid, 2014
Anthony F. Rullo   +5 more
openalex   +2 more sources

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding   +7 more
wiley   +1 more source

Profiling the proteome-wide selectivity of diverse electrophiles. [PDF]

open access: yesNat Chem
Zanon PRA   +14 more
europepmc   +1 more source

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