Results 171 to 180 of about 65,396 (291)

Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. [PDF]

Curr Res Toxicol
Klaren WD, Rivera BN, Sheppard AM, Franke K, Wikoff DS.   +4 more
europepmc   +1 more source

Parallel pathways of glutamate and ATP-mediated excitotoxicity cause significant neural cell death during ischaemia: potential for novel neuroprotective strategies

, 2013
Philipp Vermehren, Robert Fern
openalex   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Distinct features of PsbS essential for mediating plant photoprotection. [PDF]

Plant Commun
Chen L, Rodriguez-Heredia M, Hanke GT, Ruban AV.   +3 more
europepmc   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Interaction of Staphylococcus aureus di-iron Repair of Iron Centers protein with the iron-sulfur cluster assembly SUF system. [PDF]

Protein Sci
Lourenço FM, Silva LSO, Almeida MR, Folgosa F, Matias PM, Carvalho SM, Lima JC, Romão CV, Saraiva LM.   +8 more
europepmc   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

Dual mechanisms contribute to enhanced voltage dependence of an electric fish potassium channel. [PDF]

Biophys J
Todorovic J, Swapna I, Suma A, Carnevale V, Zakon H.   +4 more
europepmc   +1 more source

Glutamic acid intake by formula-fed infants: are acceptable daily intakes appropriate? [PDF]

Eur J Pediatr, 2023
Mennella JA, Smethers AD, Delahanty MT, Stallings VA, Trabulsi JC.   +4 more
europepmc   +1 more source

Exocytosis of Vesicular Zinc Reveals Persistent Depression of Neurotransmitter Release during Metabotropic Glutamate Receptor Long-Term Depression at the Hippocampal CA3–CA1 Synapse [PDF]

, 2006
Jing Qian, Jeffrey L. Noebels
openalex   +1 more source