Results 191 to 200 of about 155,970 (214)

Thermoresponsive polypeptides from pegylated poly-L-glutamates.

Biomacromolecules, 2011
The synthesis and characterization of new thermoresponsive pegylated poly-L-glutamate (poly-L-EG(x)Glu) are described. The obtained polypeptides display low critical solution temperature (LCST) behaviors in water, and the LCST can be tuned via ...
Chongyi Chen, Zhaohui Wang, Zhibo Li
semanticscholar   +1 more source

Influence of thermal processing on hydrolysis and stability of folate poly-gamma-glutamates in broccoli (Brassica oleracea var. italica), carrot (Daucus carota) and tomato (Lycopersicon esculentum).

Journal of Agricultural and Food Chemistry, 2010
The folate poly-gamma-glutamate profile, their concentrations, and hydrolysis by endogenous gamma-glutamyl hydrolase (GGH) were evaluated in broccoli, carrot and tomato. Further studies on the effect of time and temperature on folate poly-gamma-glutamate
Ann Munyaka, P. Verlinde, I. M. Mukisa, I. Oey, A. V. Van Loey, M. Hendrickx   +5 more
semanticscholar   +1 more source

CofE catalyzes the addition of two glutamates to F420-0 in F420 coenzyme biosynthesis in Methanococcus jannaschii.

Biochemistry, 2003
The protein product of the Methanococcus jannaschii MJ0768 gene has been expressed in Escherichia coli, purified to homogeneity, and shown to catalyze the GTP-dependent addition of two l-glutamates to the l-lactyl phosphodiester of 7,8-didemethyl-8 ...
Hong Li, M. Graupner, Huimin Xu, Robert H. White   +3 more
semanticscholar   +1 more source

CEREBRAL UPTAKES AND EXCHANGE DIFFUSION IN VITRO OF l‐ AND d‐GLUTAMATES

Journal of Neurochemistry, 1976
— 1. Whereas exogenous l‐glutamate enters rat brain cortex slices incubated in a glucose‐physiological saline medium by both low affinity (Km= 0.7 mm) and high affinity (Km= 27−30 μM) processes, the uptake of d‐glutamate occurs only by a low affinity (Km=
A. M. Benjamin, J. H. Quastel
semanticscholar   +1 more source

Folylpoly-gamma-glutamates as cosubstrates of 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase.

Biochemistry, 1979
N10-Formyltetrahydropteroylpoly-gamma-glutamates (N10-formyl-H4PteGlun) having n = 1, 3, 4, 5, 6, and 7 glutamyl residues have been tested as cosubstrates of the purine biosynthesis enzyme 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4 ...
J. Baggott, C. Krumdieck
semanticscholar   +1 more source

An Unconventional Method for Purifying the N-carboxyanhydride Derivatives of γ-alkyl-L-glutamates

, 1999
Common impurities in the phosgenation of α -amino acids to produce their N-carboxyanhydride (NCA) derivatives include hydrogen chloride and the hydrochloride salt of the starting amino acid.
D. Poché, M. J. Moore, Jennifer L. Bowles   +2 more
semanticscholar   +1 more source

Glutamates 99 and 107 in transmembrane helix III of subunit I of cytochrome bd are critical for binding of the heme b595-d binuclear center and enzyme activity.

Biochemistry, 2006
Cytochrome bd is a quinol oxidase of Escherichia coli under microaerophilic growth conditions. Coupling of the release of protons to the periplasm by quinol oxidation to the uptake of protons from the cytoplasm for dioxygen reduction generates a proton ...
T. Mogi, Sachiko Endou, S. Akimoto, Mayumi Morimoto-Tadokoro, H. Miyoshi   +4 more
semanticscholar   +1 more source

An amphipathic alpha-helix including glutamates 509 and 516 is crucial for membrane translocation of adenylate cyclase toxin and modulates formation and cation selectivity of its membrane channels.

Journal of Biological Chemistry, 1999
The Bordetella pertussis adenylate cyclase toxin-hemolysin (ACT or CyaA) is a multifunctional protein. It forms small cation-selective channels in target cell and lipid bilayer membranes and it delivers into cell cytosol the amino-terminal adenylate ...
Adriana Osičková, Radim Osicka, E. Maier, Roland Benz, P. Šebo   +4 more
semanticscholar   +1 more source

Coordination of Ca2+ by the pore region glutamates is essential for high-affinity dihydropyridine binding to the cardiac Ca2+ channel alpha 1 subunit.

Biochemistry, 1995
The molecular determinants for Ca2+ modulation of dihydropyridine (DHP) binding to cardiac Ca2+ channels were identified by mutational neutralization of the glutamate residues that comprise the Ca2+ channel selectivity filter. The binding activity of the
Joerg Mitterdorfer, M. J. Sinnegger, M. Grabner, Joerg Striessnig, H. Glossmann   +4 more
semanticscholar   +1 more source

AFM Study of Two-Dimensional Epitaxial Arrays of Poly(γ-l-glutamates) with Long n-Alkyl Side Chains on Graphite

, 2003
Two-dimensional (2D) arrays of poly(γ-n-alkyl l-glutamates) (PGn) on HOPG are found to be formed by casting under conditions producing submonolayer coverage.
T. Imase, A. Ohira, K. Okoshi, N. Sano, S. Kawauchi, J. Watanabe, M. Kunitake   +6 more
semanticscholar   +1 more source