Results 191 to 200 of about 226,956 (383)
Advanced Science, EarlyView.Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao +16 more
wiley +1 more source
Advanced Science, EarlyView.In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi +10 more
wiley +1 more source
Advanced Science, EarlyView.Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal +15 more
wiley +1 more source
FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine
Advanced Science, EarlyView.This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang +15 more
wiley +1 more source
Interaction between β-Fluoro-oxaloacetate and Glutamate-Aspartate Transaminase of Heart Mitochondria
, 1960 É. Kun, D.W. Fanshier, D.R. Grassetti
openalex +1 more source
1-Anilinonaphthalene-8-sulphonate, a fluorescent conformational probe for glutamate dehydrogenase [PDF]
, 1969 George H. Dodd, G. K. Radda
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Advanced Science, EarlyView.Dual‐emission carbon dot nanozymes are synthesized via microwave method. The nanozymes enhance photosynthesis corn seedlings through spectral‐matched light conversion. Their superoxide dismutase‐mimetic activity scavenges salt stress‐induced reactive oxygen species and circumvents energy‐intensive stress responses.
Chengfu Su +7 more
wiley +1 more source
The Need for Uniform Labeling Regulations for Monosodium Glutamate to Address Health Risks and Consumer Protection. [PDF]
CureusPurvez A, Valentine MC.
europepmc +1 more source
The Photoprotective Protein PsbS from Green Microalga Lobosphaera incisa: The Amino Acid Sequence, 3D Structure and Probable pH-Sensitive Residues. [PDF]
Int J Mol Sci, 2023 Ptushenko VV, Knorre DD, Glagoleva ES.
europepmc +1 more source