Advanced Science, EarlyView.To address inherent limitations in regioselectivity and catalytic efficiency of UDP‐glycosyltransferases, an integrated strategy combining free‐energy driven pocket reshaping and tunnel engineering is developed. This strategy enables UGTBL1 to bidirectional glycosylation of tyrosol, synthesizing salidroside or icariside D2 without extensive screening ...
Ziyu Zhang +7 more
wiley +1 more source
Evaluation of TOCSY mixing for sensitivity-enhancement in solid-state NMR and application of 4D experiments for side-chain assignments of the full-length 30 kDa membrane protein GlpG. [PDF]
J Biomol NMRÖster C, Chevelkov V, Lange A.
europepmc +1 more source
Piezoelectric Effect in Poly-γ-methyl-L-glutamate [PDF]
, 1966 Eiichi Fukada +2 more
openalex +1 more source
Integrating Metabolic Modulation and Nanomedicine for Cancer Immunotherapy
Advanced Science, EarlyView.Metabolic rewiring in cancer is mapped across glucose, amino acid, lipid, nucleotide, and mitochondrial pathways, with emphasis on immune regulation. The review integrates mechanisms linking these pathways to tumor progression and therapy resistance, and profiles nanomaterial platforms that both deliver therapeutics and actively reprogram ...
Xiaosu Zhou +7 more
wiley +1 more source
Structural and functional insights into extreme thermal stability and activity of two GH12 domains of a multidomain glycosidase from a hyperthermophilic euryarchaeon. [PDF]
FEBS JZayulina KS +11 more
europepmc +1 more source
The Rate of Growth of Salmonella typhimurium with Proline or Glutamate as Sole C Source
, 1962 O. Maaløe, M.H. Richmond
openalex +1 more source
Effects of Micro-injections of L-Glutamate into the Hypothalamus on Attack and Flight Behaviour in Cats [PDF]
, 1969 Jill Brody +2 more
openalex +1 more source
Surface grafting of poly (L-glutamates). 1. Synthesis and characterization
, 2001 R. H. Wieringa +7 more
semanticscholar +1 more source