Results 231 to 240 of about 65,396 (291)
Metal–phenolic network (MPN) nanoparticles with neuroprotective functions are integrated into decellularized extracellular matrix (dECM) to obtain biomimetic composite fibrous scaffold MPN@dECM NFs by electrospinning, which protects spared neurons from secondary degeneration by suppressing excitotoxicity and inflammation, and promotes directional ...
Shu Chen +4 more
wiley +1 more source
Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao +14 more
wiley +1 more source
Multiplex and multimodal mapping of variant effects in secreted proteins via MultiSTEP. [PDF]
Popp NA +14 more
europepmc +1 more source
Mapping Charge Interactions in Intrinsically Disordered Proteins
This study presents analytical models to predict intrachain distances in intrinsically disordered proteins (IDPs), accounting for charge patterning, salt concentration, and electrostatic effects. Validated against single‐molecule FRET data, a minimal‐parameter polymer model is identified that captures key interactions and chain dimensions. These models
Michael Phillips +14 more
wiley +1 more source
Transport of metformin metabolites by guanidinium exporters of the small multidrug resistance family. [PDF]
Lucero RM +3 more
europepmc +1 more source
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien +4 more
wiley +1 more source
L-Theanine Ameliorates Metabolic Dysregulation and Adverse Fetal Outcomes in a Mice Model of Gestational Obesity: Association with FXR/FGF15 Signaling. [PDF]
Huang L +8 more
europepmc +1 more source

