Results 251 to 260 of about 65,396 (291)

Reticular Chemistry: A Versatile Platform for Engineering Heterogenous Biocatalysts

Advanced Science, EarlyView.
Rational design of reticular‐based heterogeneous biocatalysts enables significant enhancement in enzyme activity recovery and even achieves catalytic performance beyond native enzymes. Abstract Reticular materials, including metal‐organic frameworks (MOFs), covalent organic frameworks (COFs), and hydrogen‐bonded organic frameworks (HOFs), have emerged ...
Si Liu, Peiji Deng, Qianfan Chen, Qijun Sun, Yanhan Wang, Hongyu Shi, Kang Liang   +6 more
wiley   +1 more source

Structural basis for α-tubulin-specific and modification state-dependent glutamylation. [PDF]

Nat Chem Biol
Mahalingan KK, Grotjahn DA, Li Y, Lander GC, Zehr EA, Roll-Mecak A.   +5 more
europepmc   +1 more source

Assessing the validity of leucine zipper constructs predicted by AlphaFold. [PDF]

Protein Sci
Mitic I, Rowell K, Litfin T, Michie KA, Jacques DA.   +4 more
europepmc   +1 more source

Interplay between ubiquitination and ADP-ribosylation and the case of dual modification ADPr-Ub. [PDF]

Essays Biochem
Zhu K, Chatrin C, Smith R, Ahel D, Ahel I.   +4 more
europepmc   +1 more source

Theanine modulation of monoamine metabolism visualized by derivatized imaging mass spectrometry. [PDF]

Sci Rep
Taira S, Abe A, Ozeki M, Shikano H, Kapoor MP, Muto M, Kobayashi S.   +6 more
europepmc   +1 more source

Experimental evolution partially restores functionality of bacterial chemotaxis network with reduced number of components. [PDF]

PLoS Genet
Kargeti M, Kalita I, Hoch S, Ratnikava M, Xu W, Ni B, Dy RL, Colin R, Sourjik V.   +8 more
europepmc   +1 more source

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved TBM motif

Waschbüsch D, Pal P, Nirujogi RS, Cavin M, Singh J, Alessi DR, Khan AR.   +6 more
europepmc   +1 more source

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The Action of Antidepressants on the Glutamate System: Regulation of Glutamate Release and Glutamate Receptors

Biological Psychiatry, 2013
Recent compelling evidence has suggested that the glutamate system is a primary mediator of psychiatric pathology and also a target for rapid-acting antidepressants. Clinical research in mood and anxiety disorders has shown alterations in levels, clearance, and metabolism of glutamate and consistent volumetric changes in brain areas where glutamate ...
L. Musazzi, G. Treccani, A. Mallei, M. Popoli   +3 more
openaire   +2 more sources

Glutamate and anxiety

European Neuropsychopharmacology, 2004
Although glutamate is a simple molecule, its actions in the limbic system and areas concerning anxiety are complex and widespread. These actions are mediated through different combinations of ionotropic and metabotropic glutamate receptors. Preclinical studies have shown that compounds active at NMDA, AMPA/kaïnate and metabotropic receptors might have ...
Veerle, Bergink, Harold J G M, van Megen, Herman G M, Westenberg   +2 more
openaire   +2 more sources

Glutamate Release

Neurochemical Research, 2015
Our aim was to review the processes of glutamate release from both biochemical and neurophysiological points of view. A large body of evidence now indicates that glutamate is specifically accumulated into synaptic vesicles, which provides strong support for the concept that glutamate is released from synaptic vesicles and is the major excitatory ...
John T, Hackett, Tetsufumi, Ueda
openaire   +2 more sources