Results 131 to 140 of about 291,286 (348)

Interface‐Adaptive Dual‐Color Hydrogel with Self‐Repairing Function and High Adhesion as Flexible Wearable Sensor for Minimally‐Invasive Monitoring Pesticide Residue in Living Crop

Advanced Science, EarlyView.
Dual‐color hydrogel TPE@Mn@ZnS@AG@PVA is prepared using b‐TPE NPs and r‐Mn@ZnS QDs as blue‐channel and red‐channel indicators, exhibits smart interface adaptability, high adhesion, good self‐repairing function, and superior response to thiophannate‐methyl, and thus acts as a flexible wearable sensor for in situ, on‐site and minimally‐destructive ...
Jianling Chen, Zihan Zhu, Yafei Li, Zizhe Wang, Wendong Wang, Hong Chen, Xuelian Xin, Zhenguo Chi, Haiyin Li   +8 more
wiley   +1 more source

Trigonelline Improves Metabolism and Cardiac Function of HFpEF Mice Via Gut Microbiome Alterations‐Mediated AMPK Activation

Advanced Science, EarlyView.
Metabolomics analyses reveal that trigonelline is markedly reduced in HFpEF hearts. Trigonelline supplementation alleviates metabolic disorders and improves cardiac function in HFpEF mice via gut microbiota‐mediated AMPK activation. Abstract Heart failure with preserved ejection fraction (HFpEF) is a prevalent end‐manifestation of cardiovascular ...
Zhe Cheng, Xiaowen Wang, Jiang Yu, Xiaorong Li, Qing Tang, Can Qu, Ding Yang, Yuanjing Li, Yong Xia, Yongzheng Guo   +9 more
wiley   +1 more source

2D Assemblies Based on a Tetraphenylethylene D,L‐Cyclic Peptide Scaffold

Angewandte Chemie, EarlyView.
A new scaffold based on four nanotube‐forming cyclic peptide units attached to a tetraphenylethene (TPE) core with pH‐dependent self‐assembly that provides light‐emitting 2D nanosheets with controlled thickness is described. Abstract Two dimensional (2D) materials and aggregation‐induced emission (AIE) fluorophores have recently gained attention due to
Alfonso Bayón‐Fernández, Alba Torrón‐Celada, Alejandro Méndez‐Ardoy, Maëva Coste, David Delgado‐Gestoso, Sébastien Ulrich, Javier Montenegro, Juan R. Granja   +7 more
wiley   +2 more sources

DFT‐Guided Design of a Multi‐Enzyme Mimetic High‐Entropy Nanozyme for Cascaded Glutathione Detection and Point‐of‐Care Testing

Advanced Science, EarlyView.
Guided by density functional theory (DFT) calculations, a MnCoNiCuZnFe‐based Prussian blue analog (HEO) is screened out. It exhibits superior peroxidase (POD)‐like activity compared to noble metal‐incorporated high‐entropy nanozymes together with excellent oxidase (OXD) and glutathione oxidase (GSHOx)‐like activities.
Hua Lin, Li Ke, Shuran Wang, Ruoke Li, Shengmin Zhou, Yueling Liu, Huan Pang   +6 more
wiley   +1 more source

Dynamics and Mechanism of Off‐ to On‐Switching in Dreiklang a Decoupled Reversibly Switchable Fluorescent Protein

Angewandte Chemie, EarlyView.
Dreiklang is a reversibly switchable fluorescent protein with a unique photohydration/dehydration mechanism. Using complementary transient absorption and femtosecond—microsecond transient IR, we follow the off‐to‐on photo‐dehydration. A multistep process is revealed, where a hundreds‐of‐picoseconds photoreaction is followed by microsecond structural ...
Anam Fatima, Yongle He, Danielle Rosenberger, Gregory M. Greetham, Partha Malakar, Andras Lukacs, Peter J. Tonge, Stephen R. Meech   +7 more
wiley   +2 more sources

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Substrate specificity and structural investigation into PepO and PepW : two peptidases from Lactobacillus rhamnosus : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]

, 2005
The proteolytic systems of lactic acid bacteria have important roles in the maturation and flavour development of cheese. Lactic acid bacteria pepetidases contribute to the taste of cheese through the production of low-molecular weight peptides and free ...
Yates, Karen Maree
core  

Flexible Crystals, Polymorph Selection and Interface Engineering for Organic Electronics: How New Discoveries and Established Knowledge Can Provide New Stimuli for Research Into Organic Semiconducting Single Crystals

Advanced Electronic Materials, EarlyView.
This work reviews recent advances in Organic Semiconducting Single Crystals (OSSCs), focusing on mechanical flexibility for robust devices, polymorph control for precise phase selection, and interface engineering with self‐assembled monolayers to improve alignment and performance.
Alessando Fraleoni‐Morgera, Siddharth Joshi, Neal Hickey, Silvano Geremia   +3 more
wiley   +1 more source

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

Angewandte Chemie, EarlyView.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler, Ingrid Richter, Katharina Dornblut, Alicia Scharf, Christian Hertweck   +4 more
wiley   +2 more sources

Alpha-aminoadipic acid: A product of lysine metabolism [PDF]

, 1948
As part of a study of protein and peptide metabolism lysine was synthesized with C14 in the ε position and resolved into the L and D isomers. 10 mg. of labeled lysine dihydrochloride (either L- or D-) and 0.66 gm.
Borsook, Henry, Deasy, Clara L., Haagen-Smit, A. J., Keighley, Geoffrey, Lowy, Peter H.   +4 more
core