Results 141 to 150 of about 154,786 (259)

Independent serum metabolomics approaches identify disrupted glutamic acid and serine metabolism in Parkinson's disease patients. [PDF]

NPJ Parkinsons Dis
Gervasoni J, Marino C, Imarisio A, Santucci L, Napolitano E, Nuzzo T, Yahyavi I, Avenali M, Cicchinelli M, Buongarzone G, Galandra C, Picascia M, Grimaldi M, Pacchetti C, Errico F, D'Ursi AM, Urbani A, Valente EM, Usiello A.   +18 more
europepmc   +1 more source

Fiber Reinforcement of Soft Spider Silk Hydrogels

Macromolecular Rapid Communications, EarlyView.
Along the development of matrices for biomedical applications, precise tuning of the biomaterial to interact with specific cell types/tissues is essential. The fabrication of fiber mesh‐reinforced soft hydrogels made of recombinant spider silk proteins allows for the adjustment of mechanical properties and hydrogel porosity, leading to improved cell ...
Christina Heinritz, Thomas Scheibel
wiley   +1 more source

Selective knockout of murine glutamic acid-rich protein 2 significantly alters dark continuous noise in rod photoreceptors. [PDF]

J Physiol
Stacks DA, Bocchero U, DeRamus ML, Nguyen MN, Messinger J, Kraft TW, Pittler SJ, Pahlberg J.   +7 more
europepmc   +1 more source

Poly(O‐Propargyl‐N‐Amino Carbamate), a Reactive Polymer to Underpin Biomedical Applications of Poly(acetylene)s

Macromolecular Rapid Communications, EarlyView.
We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh, Greta Bellio, Daniel Crisan, Amit Deb, Alba Ramil‐Bouzas, Andrey Romanyuk, Ivan Torreiro‐Leon, Ana Rey‐Rico, Paco Fernandez‐Trillo   +8 more
wiley   +1 more source

Proline-, Glutamic Acid-, Leucine-Rich Protein 1 (PELP1): Diversity, Structural Conservation, and Evolutionary Origins Across the Species. [PDF]

Int J Mol Sci
Mngomezulu N, Msweli SM, Pakala SB, Syed K.   +3 more
europepmc   +1 more source

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

Macromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh, Cyrille Boyer, Priyank V. Kumar   +2 more
wiley   +1 more source

Microfluidic Assembly of Poly(glutamic acid) Nanogels Through SPAAC Click Chemistry. [PDF]

Pharmaceutics
Mastella P, Luin S.
europepmc   +1 more source

Underlying Mechanisms of the Treatment Efficacy of (R, S)‐Ketamine for Post‐Traumatic Stress Disorder and Depression: A Review

Medicine Advances, EarlyView.
Research shows that (R, S)‐ketamine and its stereoisomers effectively reduce symptoms of post‐traumatic stress disorder (PTSD) and treatment‐resistant depression, with (R)‐ketamine offering similar benefits with fewer side effects. Evidence highlights specific neural circuits and regions, including the dentate gyrus, prefrontal cortex, vCA3, dorsal ...
Thomas Edward Cutting, Richard Evans Hartman   +1 more
wiley   +1 more source

Amphiphilic Poly(γ-glutamic acid) Derivatives for Delivering Doxorubicin in Cancer Cells. [PDF]

Macromol Biosci
Dorost P, Morais MRG, Guimarães SC, Pêgo AP, García-Alvarez M, Martínez de Ilarduya A.   +5 more
europepmc   +1 more source

The effects of seasonality and parasitism on diet and habitat selection in the common periwinkle

Oikos, EarlyView.
The common periwinkle Littorina littorea is an ecologically important grazer, known for its strong influence on algal communities and its role in structuring ecosystems. It serves as the first intermediate host for several trematode species in the Baltic Sea, especially for the fluke Cryptocotyle lingua.
Friederike Gronwald, Claudia Bommarito, Dakeishla M. Díaz‐Morales, Alessandro Manfrin, Cindy Martinez Reyes, Milen Nachev, Bernd Sures, Florian Weinberger   +7 more
wiley   +1 more source