Results 41 to 50 of about 253,703 (290)

A Comparison of the Mechanical Properties of ECM Components and Synthetic Self‐Assembling Peptides

Advanced Healthcare Materials, EarlyView.
Self‐assembling peptide hydrogels are increasingly utilized in biomedical applications. The authors review the key mechanical properties of these structures across multiple size scales and compare them to that of native extracellular matrix components, which are found to display a much wider range of structural attributes.
Alex Hartley, Philip Michael Williams, Alvaro Mata   +2 more
wiley   +1 more source

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, EarlyView.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

Glutamate biosynthesis in Bacillus azotofixans. 15N NMR and enzymatic studies [PDF]

, 1988
Pathways of ammonia assimilation into glutamic acid in Bacillus azotofixans, a recently characterized nitrogen-fixing species of Bacillus, were investigated through observation by NMR spectroscopy of in vivo incorporation of 15N into glutamine and ...
Kanamori, Keiko, Roberts, John D., Weiss, Richard L.   +2 more
core  

Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma

Advanced Materials, EarlyView.
A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura, Alessio Malfanti, Ana I Matos, Carina Peres, Ana Armiñán, Aroa Duro‐Castaño, Inmaculada Conejos‐Sánchez, María Medel, Snežana Đorđević, Paula Carrascosa, Bárbara Carreira, Rita C Acúrcio, Helena Xavier‐Ferreira, Alberto Hernández‐Barranco, Elena Castellano, Esther Roselló, José C. Machado, Héctor Peinado, María J. Vicent, Helena F. Florindo   +19 more
wiley   +1 more source

Synthesis and properties of lipoamino acid/fatty acid mixtures. Influence of the amphiphilic structure. [PDF]

, 2009
The acylation of amino acids by acid chlorides with from 8 to 12 carbon atoms, in alkaline aqueous medium following Shotten-Baumann reaction, results in sodium salts of Nα-acylamino acids and fatty acids mixture. These lastest are present in proportion
Alric, Isabelle, Blanco, Jean-François, Mouloungui, Zéphirin, Rondel, Caroline, Silvestre, Françoise   +4 more
core   +1 more source

A Library of Polyphenol‐Amino Acid Condensates for High‐Throughput Continuous Flow Production of Nanomedicines with Ultra‐High Drug Loading

Advanced Materials, EarlyView.
A scalable and flexible library of natural, renewable tea polyphenol, and amino acid condensate colloidal spheres, synthesized via a one‐step process, facilitates the preparation of ultra‐high drug‐loading nanomedicines with precise size control and uniform dispersion using continuous‐flow microfluidics.
Zeng Yi, Xiaomin Ma, Qiulan Tong, Lei Ma, Yunfei Tan, Danni Liu, Chaoliang Tan, Junze Chen, Xudong Li   +8 more
wiley   +1 more source

Amyloid‐Templated Ceria Nanozyme Reinforced Microneedle for Diabetic Wound Treatments

Advanced Materials, EarlyView.
This work demonstrates an effective strategy for synthesizing high‐catalytic and stable nanozymes, and introduces the first example of amyloid‐ceria nanozymes reinforced microneedle which features a complex, synergistic catalytic behavior combining superoxide dismutase and catalase‐like activities, promoting to remodel the infection microenvironment in
Qize Xuan, Jiazhe Cai, Yuan Gao, Xinchi Qiao, Tonghui Jin, Mohammad Peydayesh, Jiangtao Zhou, Qiyao Sun, Lijian Zhan, Bin Liu, Ping Wang, Hui Li, Chao Chen, Raffaele Mezzenga   +13 more
wiley   +1 more source

Smart Dust for Chemical Mapping

Advanced Materials, EarlyView.
This review article explores the advancement of smart dust networks for high‐resolution spatial and temporal chemical mapping. Comprising miniature, wireless sensors, and communication devices, smart dust autonomously collects, processes, and transmits data via swarm‐based communication.
Indrajit Mondal, Hossam Haick
wiley   +1 more source

Polydiacetylene‐Crosslinked Oligosiloxanes for Dual‐Mode Temperature Sensing

Advanced Materials Technologies, EarlyView.
This work combines polydiacetylenes with oligosiloxanes for enhanced solubility and processability. The hybrid material showcases reversible thermochromism (25–47 °C) and dual‐mode temperature sensing via color shifts and capacitance changes. With improved properties, this work paves the way for scalable optoelectronic flexible and conformable sensors.
Fatemeh Motaghedi, Lina Rose, Amit K. Sur, Garima Garg, Audithya Nyayachavadi, Mohammed Jalal Ahamed, Tricia Breen Carmichael, Simon Rondeau‐Gagné   +7 more
wiley   +1 more source

Synthesis of Unnatural Amino Acids via β‐Aminoaldehyde C–H Arylation using HAT‐Metallaphotoredox Catalysis

Advanced Synthesis &Catalysis, EarlyView.
Abstract Unnatural amino acids play a crucial role in advancing protein engineering and drug development. In this study, we present the synthesis of a series of γ‐aryl‐keto‐α‐amino acids through the direct C−H arylation of readily accessible β‐aminoaldehydes and aryl bromides, promoted by hydrogen atom transfer combined with metallaphotoredox catalysis.
Mariana dos S. Dupim, Bruno M. da S. Santos, Lívia C. R. M. da Frota, Fernanda G. Finelli   +3 more
wiley   +1 more source