Results 61 to 70 of about 253,703 (290)

The synthesis and characterization of polypeptide-adriamycin conjugates and its complexes with adriamycin. Part I [PDF]

, 1985
Poly(α-l-glutamic acid) (PGA) was grafted with amino acid and oligopeptide spacers up to 5 amino acids with the use of N,N'-carbonyldiimidazole and 2,3-dihydro-1,2-benz-isothiazole-3-on-1, 1-dioxide (saccharin) as an additive, and these polypeptides were
Eenink, M.J.D., Feijen, J., Heeswijk, W.A.R., Hoes, C.J.T., Potman, W., Stoffer, T.   +5 more
core   +2 more sources

Immunostimulatory Hydrogel with Synergistic Blockage of Glutamine Metabolism and Chemodynamic Therapy for Postoperative Management of Glioblastoma

Advanced Science, EarlyView.
To address the challenge of postoperative recurrence, Combo Gel, a peptide‐based hydrogel that integrates glutamine metabolism modulation with chemodynamic therapy (CDT) is engineered. This innovative system, containing CB‐839 and copper peptide nanoparticles (Cu‐His NPs), enhances CDT's efficacy and promotes immunogenic cell death, thereby ...
Yiran Guo, Tianhe Jiang, Sen Liang, Anhe Wang, Jieling Li, Yi Jia, Qi Li, Jian Yin, Shuo Bai, Junbai Li   +9 more
wiley   +1 more source

Pharmacological characteristics of receptors for L-glutamic acid and its derivatives on the giant neurones of Achatina fulica Ferussac. (1) Effects of L-glutamic acid and its agonists on snail neurones. (2) Pharmacological characteristics of an outward current produced by β-hydroxy-L-glutamic acid on a snail neurone. [PDF]

, 1996
博士論文 (Doctoral dissertation)(1) Effects of L-glutamic acid and its agonists on snail neurones.(2) Pharmacological characteristics of an outward current produced by β-hydroxy-L-glutamic acid on a snail neurone.doctoral ...
397073, 張, 唯
core  

Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes [PDF]

, 1997
Hen egg-white lysozyme has long been the paradigm for enzymatic glycosyl hydrolysis with retention of configuration, with a protonated carboxylic acid and a deprotonated carboxylate participating in general acid-base catalysis.
Blake C. C. F., C−, Davies G. J., Ford L. O., Henrissat B., Iseli B., Johnson L. N., Jones T. A., Kirby A., Knapp S., Kobayashi S., Koshland D. E., Perrakis A., Phillips D. C., Piszkiewicz D., Rao V. H., Rozeboom H. J., Sinnot M. L., Strynadka N. C. J., Sulzenbacher G., Terwisscha van Scheltinga A. C., Terwisscha van Scheltinga A. C., Terwisscha van Scheltinga A. C., Tews I., Thunnissen A. M. W. H., Tronrud D. E., van Roey P., Vårum K. M., Weaver L. H.   +28 more
core   +3 more sources

1000 fold Ultra‐Photosensitized Fluorescent Protein Mimics Toward Photocatalytic Proximity Labeling and Proteomic Profiling Functions

Advanced Science, EarlyView.
While natural fluorescent proteins are widely used for imaging, in this work, an ultra‐photosensitized fluorescent protein mimic (upsFP) tag is developed to enable its protein proximity labeling (PPL) function and demonstrate its proteomic applications. Abstract Photosensitizing fluorescent proteins (FP) (e.g.
Rui Sun, Yanan Huang, Huan Feng, Nan Zhao, Wang Wan, Di Shen, Bowen Zhong, Yukui Zhang, Xin Zhang, Qun Zhao, Lihua Zhang, Yu Liu   +11 more
wiley   +1 more source

Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors

ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022
Next‐generation diagnostics: Nanocarbon‐based field effect transistors (NC‐FETs) use incoming target analytes to impart a gating effect on conductance. Here, we review the operational mechanisms behind NC‐FETs, the fabrication and functionalisation of NC‐FETs with receptor biomolecules and downstream biosensing applications.
Chang‐Seuk Lee, Rebecca E. A. Gwyther, Mark Freeley, Dafydd Jones, Matteo Palma   +4 more
wiley   +1 more source

A reappraisal of nitrogen-to-protein conversion factors in cassava roots. [S10-05] [PDF]

, 2012
A study was conducted comparing the amino acid profiles of 10 commercial varieties (COL) and 15 clones with the highest levels of nitrogen (HIN) over two years of harvests. The highest nitrogen values detected in roots to date are close to 1.30%.
Ceballos, Hernan, Dufour, Dominique, Hershey, Clair, Morante, Nelson, Morel, Gilles, Reynes, Max, Ricci, Julien, Sanchez, Teresa   +7 more
core  

Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: evidence from discordant monozygotic twins [PDF]

, 2015
Although a higher protein intake, particularly from vegetable sources, has been shown to be associated with higher bone mineral density (BMD) the relative impact of specific amino acids (AA) on BMD and risk of osteoporosis remains to be determined ...
Ammann, Andrew, Arden, Arnett, Beasley, Beasley, Bingham, Bingham, Bingham, Black, Buclin, Cherkas, Chevalley, Conigrave, Crawley, Darling, Dawson-Hughes, Fenton, Fini, Fujita, Goel, Hall, Hannan, Holmes, Hu, Ishihara, Jesudason, Kroke, Laudermilk, Liu, Massey, Melendez-Hevia, Munger, Promislow, Rapuri, Rennie, Ryder, Sahni, Sahni, Shea, Teucher, Weikert, Welch, Welch, Yang, Zhang   +45 more
core   +1 more source

How Do Glycine‐Induced Bent Structures Influence Hierarchical Nanostructuring and Suprastructural Handedness in Short Peptide Assembly?

Advanced Science, EarlyView.
How does flexible and achiral glycine affect suprastructural handedness in peptide self‐assembly? A series of short peptides containing glycine is designed, and different molecular conformations caused by varying the position of glycine can lead to different hydrogen bonding patterns upon forming β‐sheets, eventually resulting in variations in their ...
Xinfeng Ju, Kai Qi, Yan Wang, Limin Zhang, Yingyu Wang, Muhan Wang, Jiqian Wang, Jun Zhang, Jian R. Lu, Hai Xu, Yurong Zhao   +10 more
wiley   +1 more source

Effects of long-term postgastric infusion of casein or glutamic acid on small intestinal starch digestion, energy balance, body composition, and metabolic fates of luminally assimilated glucose carbon in cattle [PDF]

Small intestinal starch digestion (SISD) in ruminants is limited, but SISD can be improved by postruminal supply of casein or glutamic acid. There are no reports on the effects of increases in SISD in response to greater postgastric nutrient flows from ...
Acharya, Subash
core   +1 more source