Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li +10 more
wiley +1 more source
Effects of glutamic-lactic acid mixture and its combination with aspargic acid and with alanine on maturation rate of salted Baltic herring [PDF]
Glutamic-lactic acid mixture and its combination with aspargic acid acid with alanine were used to obtain effect on maturation rate of salted Baltic herring. Those substances were added in amount of 0.17% each per fish weight.
M. Jasińska, M. Żygadło
doaj +3 more sources
The conversion of citrulline to arginine in kidney [PDF]
Glycocyamine is formed in the kidney by the transfer of the amidine group of arginine to the nitrogen atom of glycine. In the study of this reaction it was observed that glycocyamine was also formed from citrulline and glycine.
Borsook, Henry, Dubnoff, Jacob W.
core
Evidence for a GABAergic system in rodent and human testis: Local GABA production and GABA receptors [PDF]
The major neurotransmitter of the central nervous system, gamma-aminobutyric acid (GABA), exerts its actions through GABA(A), GABA(B) and GABA(C) receptors.
Calandra, Ricardo S. +7 more
core +2 more sources
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
IMMUNOLOGIC PREVENTION OF IDDM BY ORAL ADMINISTRATION OF GLUTAMIC ACID DECARBOXYLASE [PDF]
We have Investigated the preventive effects of oral administration of isolated E.coli ghttam'tc acid decarboxylase (GAD) in animal models. Based on our results, the blood glucose levels were reduced by oral administration of GAD to rats 14
L. Yazdchi Mari +1 more
doaj +2 more sources
Free amino acids in a cave beetle \u3cem\u3eDarlingtonea kentuckensis\u3c/em\u3e Valentine (Coleoptera: Carabidae) [PDF]
Free amino acids of Darlingtonea kentuckensis were investigated by two-dimensional, thin-layer chromatography on Silica Gel G. Thirteen amino acids which could be identifìed (alanine, glutamic acid, glycine, histidine, isoleucine and/or leucine, lysine ...
Sperka, R. J.
core +2 more sources
Gad65 is recognized by t-cells, but not by antibodies from nod-mice [PDF]
Since the 64kDa-protein glutamic acid decarboxylase (GAD) is one of the major autoantigens in T-cell mediated Type 1 diabetes, its relevance as a T-cell antigen needs to be clarified. After isolation of splenic T-cells from non-obese diabetic (NOD) mice,
Alzari PM +28 more
core +1 more source
This review discusses cellulose‐based hydrogels technology, analyzes their application progress in physiological signal monitoring, and explores the effects of pretreatment, crosslinking, and molding methods on gel performance, to provide valuable insights into the efficient utilization of plant fibers and the environmentally friendly development of ...
Zhiming Wang +8 more
wiley +1 more source
pH‐Tunable Material Properties of Glycine‐Rich Condensates from Tick Bioadhesive
This work studies the influence of pH on the phase separation behavior of a disordered glycine‐rich protein found in tick bioadhesive. The results show profound impact on the propensity of coacervation, condensate microstructure and viscosity, amphiphilicity of the peptides, and effective encapsulation of therapeutic molecules.
Manali Nandy +5 more
wiley +1 more source

