Results 81 to 90 of about 5,254,114 (398)
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
High-pressure torsion processing of serine and glutamic acid: Understanding mechanochemical behavior of amino acids under astronomical impacts [PDF]
Advanced Engineering Materials, vol. 26, p. 2302267, 2024Astronomical impacts by small solar system bodies (meteoroids, asteroids, comets, and transitional objects) are considered a mechanism for delivering amino acids and their polymerization to proteins in early Earth conditions. High-pressure torsion (HPT) is a new methodology to simulate such impacts and clarify the behavior of biomolecules.
arxiv +1 more source
Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies.
JAMA Neurology, 2015 IMPORTANCE Little is known of glutamic acid decarboxylase antibodies (GAD-abs) in the paraneoplastic context. Clinical recognition of such cases will lead to prompt tumor diagnosis and appropriate treatment.
H. Ariño +12 more
semanticscholar +1 more source
Effect of Tryptophan and Glutamic Acid on Morphological Traits of Iranian and Afghan Saffron [PDF]
, 2023 In order to investigate the effect of amino acids tryptophan and glutamic acid on the morphological traits of saffron medicinal plant, a factorial experiment was conducted in the form of a randomized complete block design in three replications in 2018 in
Kheiry, Azizollah +2 more
core +2 more sources
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Quantification of Glutamate and Aspartate by Ultra-High Performance Liquid Chromatography
Molecules, 2018 Glutamic and aspartic acid fulfil numerous functions in organisms. They are proteinogenic amino acids, they function as neurotransmitters, and glutamic acid links the citrate cycle with amino acid metabolism. In addition, glutamic acid is a precursor for
Carlos Agius +3 more
doaj +1 more source
Mechanical stretching of amyloid Abeta11-42 fibrils using steered molecular dynamics [PDF]
arXiv, 2021 Mechanical strength of amyloid beta fibrils has been known to be correlated with neuronal cell death. Here, we resorted to steered molecular dynamics (SMD) simulations to mechanically stretch a single S-shape amyloid beta Abeta11-42 dodecamer fibril in vacuum.
arxiv
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Effects of glutamic-lactic acid mixture and its combination with aspargic acid and with alanine on maturation rate of salted Baltic herring [PDF]
Acta Ichthyologica et Piscatoria, 1995 Glutamic-lactic acid mixture and its combination with aspargic acid acid with alanine were used to obtain effect on maturation rate of salted Baltic herring. Those substances were added in amount of 0.17% each per fish weight.
M. Jasińska, M. Żygadło
doaj +3 more sources
FEBS Open Bio, Volume 15, Issue 4, Page 573-579, April 2025.Yeast surface display (YSD) uses genetically modified yeast to immobilize recombinant enzymes on the cell surface. To quantify the efficiency of YSD, β‐lactamase was fused to selected cell wall proteins and enzyme activity was measured spectrophotometrically at 482 nm using nitrocefin as substrate. This system enables the monitoring of enzyme activity,
Tea Martinić Cezar +5 more
wiley +1 more source