Results 21 to 30 of about 26,552,545 (120)

A Structure‐Activity Relationship Study of Bimodal BODIPY‐Labeled PSMA‐Targeting Bioconjugates

ChemMedChem, Volume 16, Issue 16, Page 2535-2545, August 19, 2021., 2021
Have it both ways: By structure–activity relationship studies, a bimodal imaging probe combining fluorescence with nuclear imaging based on BODIPY dyes with high affinity for the prostate‐specific membrane antigen (PSMA) has been identified. The bimodal conjugate demonstrated PSMA‐specific uptake in prostate cancer cells with accumulation in the cell ...
Tobias Stemler, Caroline Hoffmann, Ina M. Hierlmeier, Stephan Maus, Elmar Krause, Samer Ezziddin, Gregor Jung, Mark D. Bartholomä   +7 more
wiley   +1 more source

A mutation in amino acid permease AAP6 reduces the amino acid content of the Arabidopsis sieve elements but leaves aphid herbivores unaffected [PDF]

, 2010
The aim of this study was to investigate the role of the amino acid permease gene AAP6 in regulating phloem amino acid composition and then to determine the effects of this altered diet on aphid performance.
Newbury, H. J., Hunt, E. (Emma), Gattolin, Stefano, Pritchard, J. (Jeremy), Tseng, Hua-Ming, Bale, J. S. (Jeffrey S.), Barrett, D. A. (David A.)   +6 more
core   +2 more sources

Bioinert, Stealth or Interactive: How Surface Chemistry of Nanocarriers Determines Their Fate In Vivo

Advanced Functional Materials, Volume 31, Issue 34, August 20, 2021., 2021
The fate of nanocarriers (NCs) in vivo is mainly determined by their surface chemistry. Various surface modifications are investigated to either prevent or promote the interaction of NCs with the biological environment. However, in future, the potential of NCs lies in smart approaches to balance, combine, or transform inert to interactive NC surfaces ...
Julian David Friedl, Valeria Nele, Giuseppe De Rosa, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

Rapid Identification of Chemical Constituents in Hericium erinaceus Based on LC‐MS/MS Metabolomics

Journal of Food Quality, Volume 2021, Issue 1, 2021., 2021
Hericium erinaceus is a precious edible and medicinal fungus with high nutritional value. It has many functions, such as enhancing immunity, antitumor antioxidation, antihyperglycemic, antihyperlipidemic, and protecting gastric mucosa. However, there are few researches about the H. erinaceus compounds.
Fei Yang, Honglin Wang, Guoquan Feng, Sulan Zhang, Jinmei Wang, Lili Cui, Xiao-zhi Tang   +6 more
wiley   +1 more source

Gardnerella vaginalis and Neisseria gonorrhoeae Are Effectively Inhibited by Lactobacilli with Probiotic Properties Isolated from Brazilian Cupuaçu (Theobroma grandiflorum) Fruit

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
In recent years, certain Lactobacillus sp. have emerged in health care as an alternative therapy for various diseases. Based on this, this study is aimed at evaluating in vitro the potential probiotics of five lactobacilli strains isolated from pulp of cupuaçu fruit fermentation against Gardnerella vaginalis and Neisseria gonorrhoeae.
Nathan das Neves Selis, Hellen Braga Martins de Oliveira, Yan Bento dos Anjos, Hiago Ferreira Leão, Beatriz Almeida Sampaio, Thiago Macêdo Lopes Correia, Mariane Mares Reis, Thamara Louisy Santos Brito, Carolline Florentino Almeida, Larissa Silva Carvalho Pena, Laís Ferraz Brito, Roberta Maria Ornelas, Tizá Teles Santos, Guilherme Barreto Campos, Jorge Timenetsky, Mariluze Peixoto Cruz, Andréa Miura da Costa, Regiane Yatsuda, Ana Paula Trovatti Uetanabaro, Lucas Miranda Marques, Nazir Ahmad Khan   +20 more
wiley   +1 more source

Morphophysiological and Comparative Metabolic Profiling of Purslane Genotypes (Portulaca oleracea L.) under Salt Stress

BioMed Research International, Volume 2020, Issue 1, 2020., 2020
Purslane, a fleshy herbaceous plant, plays a pivotal role in various preventive and therapeutic purposes. To date, no report has documented the consequence of salt stress on metabolite accumulation in purslane. Herein, we proposed an insight into the metabolic and physiological traits of purslane under saline stress environments. The gas chromatography‐
Shah Zaman, Muhammad Bilal, Hongmei Du, Shengquan Che, Ashok Nadda   +4 more
wiley   +1 more source

Optimization of the dilute maleic acid pretreatment of wheat straw [PDF]

, 2009
Background In this study, the dilute maleic acid pretreatment of wheat straw is optimized, using pretreatment time, temperature and maleic acid concentration as design variables. A central composite design was applied to the experimental set up.
Hendrik H Beeftink, Elinor L Scott, Johan PM Sanders, Scott, E.L., Sanders, J.P.M., Kootstra, A.M.J., Sanders Johan PM, Beeftink, H.H., A Maarten J Kootstra, Scott Elinor L, Kootstra A Maarten J, Beeftink Hendrik H   +11 more
core   +1 more source

Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]

, 2014
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Peppiatt-Wildman, Claire M., Wildman, Scott S.P., Dunn, Kadeshia, Kelley, Stephen P., Wildman, Scott S. P.   +4 more
core   +1 more source

Root phloem-specific expression of the plasma membrane amino acid proton co-transporter AAP3 [PDF]

, 2004
Amino acids are regarded as the nitrogen ‘currency’ of plants. Amino acids can be taken up from the soil directly or synthesized from inorganic nitrogen, and then circulated in the plant via phloem and xylem.
Sakiko Okumoto, Leister, D., Frommer, Wolf B., Wolf B. Frommer, Okumoto, Sakiko, FISCHER, Wolf N, Stierhof, York Dieter, Frommer, W. B., Stierhof, Y., Stierhof, Y.-D., Fischer, W., Wolfgang Koch, Koch, W., FROMMER, Wolf B, Mechthild Tegeder, Fischer, Wolf N., Leister, Dario, Wolf N. Fischer, Koch, Wolfgang, Okumoto, S., Tegeder, Mechthild, Dario Leister, Tegeder, M., Biehl, A., York Dieter Stierhof, Alexander Biehl, Biehl, Alexander, Fischer, W. N., Frommer, W.   +28 more
core   +2 more sources

Amino acid uptake in Arabidopsis [PDF]

, 2008
Nitrogen (N) is essential for all living organisms and is considered to be the limiting factor for plant growth in many ecosystems. Although generally believed to rely on mineral N to fulfill their N needs, plants have also been found to access organic N
Svennerstam, Henrik
core   +1 more source