Results 231 to 240 of about 760,519 (335)

Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer   +4 more
wiley   +1 more source

Glutamine relieves feed restriction-induced ruminal epithelial function damage through histone lysine lactylation in yaks. [PDF]

open access: yesJ Anim Sci Biotechnol
Yue Z   +9 more
europepmc   +1 more source

Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs

open access: yesAdvanced Healthcare Materials, EarlyView.
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller   +5 more
wiley   +1 more source

Targeting cancer glutamine dependency with a first-in-class inhibitor of the mitochondrial glutamine transporter SLC1A5_var. [PDF]

open access: yesNat Commun
Sung Y   +16 more
europepmc   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

open access: yesAdvanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente   +5 more
wiley   +1 more source

Hybrid Scaffolds Decouple Biochemical & Biophysical Regulation of Cell Phenotype

open access: yesAdvanced Healthcare Materials, EarlyView.
Replicating tissue‐specific extracellular matrix is crucial for understanding its role in disease. This work demonstrates independent control over stiffness, composition and 3D collagen architecture using hybrid scaffolds: patterned collagen perfused with defined hydrogels.
Xinyuan Song   +17 more
wiley   +1 more source

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