Results 1 to 10 of about 223,254 (334)

Does occupational exposure to solvents and pesticides in association with glutathione S-transferase A1, M1, P1, and T1 polymorphisms increase the risk of bladder cancer? The Belgrade case-control study. [PDF]

PLoS ONE, 2014
OBJECTIVE: We investigated the role of the glutathione S-transferase A1, M1, P1 and T1 gene polymorphisms and potential effect modification by occupational exposure to different chemicals in Serbian bladder cancer male patients.
Marija G Matic, Vesna M Coric, Ana R Savic-Radojevic, Petar V Bulat, Marija S Pljesa-Ercegovac, Dejan P Dragicevic, Tatjana I Djukic, Tatjana P Simic, Tatjana D Pekmezovic   +8 more
doaj   +2 more sources

Reversal of hypermethylation and reactivation of glutathione -transferase pi 1 gene by curcumin in breast cancer cell line

Tumor Biology, 2017
One of the mechanisms for epigenetic silencing of tumor suppressor genes is hypermethylation of cytosine residue at CpG islands at their promoter region that contributes to malignant progression of tumor.
Umesh Kumar, Ujjawal Sharma, Garima Rathi   +2 more
doaj   +2 more sources

Glutathione S-Transferase Enzymes in Plant-Pathogen Interactions

Frontiers in Plant Science, 2018
Plant glutathione S-transferases (GSTs) are ubiquitous and multifunctional enzymes encoded by large gene families. A characteristic feature of GST genes is their high inducibility by a wide range of stress conditions including biotic stress.
Gábor Gullner, Tamas Komives, Lóránt Király, Peter Schröder   +3 more
doaj   +2 more sources

Glutathione S-transferase M1 and T1 null polymorphisms and risk of oral submucous fibrosis: a meta-analysis of South Asian populations [PDF]

BMC Oral Health
Background Oral submucous fibrosis (OSMF) is a precancerous condition prevalent in individuals who habitually consume areca nut products. While environmental risk factors play a significant role in OSMF, genetic predisposition—particularly involving ...
Paria Motahari, Negin Neshanifard
doaj   +2 more sources

A Glutathione S-Transferase Pi Molecular Glue Tethers Splicing Factors and Remodels Cell Metabolism. [PDF]

J Am Chem Soc
Leace DM, Ware ML, Murtagh O, Tsai HK, Chang CY, Hsu KL.   +5 more
europepmc   +3 more sources

Characterization of the E26H Mutant Schistosoma japonicum Glutathione S-Transferase. [PDF]

Proteins
Mótyán JA, Veres ÁN, Tőzsér J.
europepmc   +3 more sources

The expression of GST isoenzymes and p53 in non-small cell lung cancer.

Folia Histochemica et Cytobiologica, 2010
This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase alpha, pi, mu, theta and p53 in non-small cell lung carcinoma and normal lung tissue from 50 patients.
MĂźzeyyen Ozhavzali, UlkĂź Yazici, Funda Demirag, Mehtap Aydin, Serpil OguztĂźzun, Murat Kiliç, Mesude Iş can   +6 more
doaj   +1 more source

The Role of Glutathione-S Transferase in Psoriasis and Associated Comorbidities and the Effect of Dimethyl Fumarate in This Pathway

Frontiers in Medicine, 2022
Psoriasis vulgaris is a chronic inflammatory skin disease characterized by well-demarcated scaly plaques. Oxidative stress plays a crucial role in the psoriasis pathogenesis and is associated with the disease severity.
Elena Campione, Sara Mazzilli, Monia Di Prete, Monia Di Prete, Annunziata Dattola, Terenzio Cosio, Daniele Lettieri Barbato, Daniele Lettieri Barbato, Gaetana Costanza, Caterina Lanna, Valeria Manfreda, Ruslana Gaeta Schumak, Francesca Prignano, Filadelfo Coniglione, Fabrizio Ciprani, Katia Aquilano, Luca Bianchi   +16 more
doaj   +1 more source

Genetic polymorphisms of glutathione S-transferase Mu 1, glutathione S-transferase theta 1, and glutathione S-transferase P1 in oral squamous cell carcinoma: A case-control study in Iranian population

Journal of Orofacial Sciences, 2015
Background: Gene variability related to activation and detoxification of procarcinogens affects the susceptibility to oral squamous cell carcinoma (OSCC).
Bahram Yaghmaei, Kaveh Yaghmaei, Mohammad Jafarian, Shima Golmohammadi   +3 more
doaj   +1 more source

Glutathione S-transferase M1 and T1 polymorphisms and the risk of mild hepatotoxicity induced by carbamazepine in a tunisian population study

BMC Neurology, 2018
Background The aim of this study was to evaluate whether the glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) null alleles may contribute to carbamazepine-induced hepatotoxicity.
Chahra Chbili, Anis Hassine, Neila Fathallah, Manel Nouira, Salma Naija, Sofiene Ben Ammou, Saad Saguem   +6 more
doaj   +1 more source