Results 31 to 40 of about 21,415,121 (192)

Genetic polymorphisms of glutathione S transferase and cervical intraepithelial neoplasia

Romanian Journal of Laboratory Medicine, 2016
Aim: The present study aim to analyze the relationship between GST M/T genotypes of glutathione S-transferases and cervical intraepithelial neoplasia.
Daniel Mureșan, Cătană Andreea, Popp Radu Anghel, Dumitraș Diana Elena, Stamatian Florin, Buzoianu Anca Dana, Rotar Ioana Cristina   +6 more
doaj   +1 more source

Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate [PDF]

, 2008
Epidemiological studies suggest that people who consume more than one portion of cruciferous vegetables per week are at lower risk of both the incidence of prostate cancer and of developing aggressive prostate cancer but there is little understanding of ...
Richard Y Ball, Amy V Gasper, David A Barrett, Catharine A. Ortori, Richard F Mithen, Richard F. Mithen, Catharine A Ortori, Amy V. Gasper, Paul W. Needs, Traka, Maria H., Maria Traka, Ball, Richard Y., Traka, Maria, Barrett, David A., David A. Barrett, Jones, Alexandra M. E., Antonietta Melchini, Chantry, Andrew, Ortori, Catharine A., Bacon, James R., Mills, Robert D., Richard Y. Ball, Melchini, Antonietta, Frost, Victoria, Victoria Frost, Paul W Needs, Robert D. Mills, Needs, Paul W., James R. Bacon, James R Bacon, Jones, Alexandra M., Gasper, Amy V., Alexandra M. E. Jones, Andrew Chantry, Alexandra M E Jones, Mithen, Richard F., Robert D Mills   +36 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

The significance of reduced glutathione and glutathione S-transferase during chemoradiotherapy of locally advanced cervical cancer

Medicina, 2014
Background and objective: To determine changes in reduced glutathione (GSH) and glutathione S-transferase (GST) during neoadjuvant chemotherapy followed by concurrent chemoradiation for patients with stage IIB–IIIB cervical cancer, and to evaluate their ...
Lina Daukantienė, Birutė Kazbarienė, Konstantinas Povilas Valuckas, Janina Didžiapetrienė, Aurelija Krikštaponienė, Eduardas Aleknavičius   +5 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes [PDF]

, 2008
A retrospective study on healthy, unrelated subjects was conducted in order to estimate population glutathione-S-transferases (GST) genotype frequencies in Slovak population of men and compare our results with already published data (GSEC project)^1^.
Monika Sivoňová, Tatiana Matáková, Iveta Waczulíková, Peter Račay, Dušan Dobrota, Jozef Hatok, Ján Kliment   +6 more
core  

Glutathione S-Transferase pi (GSTP1) [PDF]

, 2010
Deep insight on Glutathione S-Transferase pi (GSTP1)
I Meiers, Meiers, I
core   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Stabilization of the Interaction of the Compunds of Mallotus paniculatus Müll.Arg. on Gluthations S-Transferase (GSTs)

Berkala Kedokteran, 2021
: Gluthathione s-transferases (GSTs) play an important role against carcinogens, therapeutic drugs, and various types of cellular oxidative damage.
Samsul Hadi
doaj   +1 more source