Results 51 to 60 of about 16,021,849 (210)
The role of glutathione transferases in TNT detoxification [PDF]
, 2012 Glutathione transferases (GSTs) are multi-functional enzymes with an important role in plant biochemical mechanisms of xenobiotic detoxification. The GSTs have been extensively studied due to their ability to detoxify herbicides; recently they have been ...
Gunning, Vanda
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Serum total glutathione-s-transferase levels in oral cancer [PDF]
, 2008 We conducted a study wherein serum total glutathione-s-transferase levels were measured in patients (n = 27) with various stages of biopsy proven oral cancer (squamous cell carcinoma) and age and sex matched healthy human volunteers (n=10).
Prabhu, Krishnananda +1 more
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Glutathione S-conjugates as prodrugs to target drug-resistant tumors
Frontiers in Pharmacology, 2014 Living organisms are continuously exposed to xenobiotics. The major phase of enzymatic detoxification in many species is the conjugation of activated xenobiotics to reduced glutathione (GSH) catalyzed by the glutathione-S-transferase (GST).
Emma E. Ramsay, Pierre J. Dilda
doaj +1 more source
The influence of glutathione S-transferases M1 and M3 on the development of bladder cancer [PDF]
Problem: Cigarette smoking is the most important risk factor of transitional cell carcinoma of the urinary bladder. The effect of the glutathione S- transferases M1 (GSTM1) and M3 (GSTM3) on the influence of this risk factor was investigated.
Golka, Klaus +3 more
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Journal of Pharmacological Sciences, 2010 We investigated the effects of treatment with trimethyltin (TMT) on the expression of glutathione-related enzymes in mouse hippocampus. TMT promoted the expression of glutathione S-transferase (GST) Ya/Yc mRNA, and GSTA2 protein, but not that of ...
Reiko Nagashima +4 more
doaj +1 more source
A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes
, 2008 A retrospective study on healthy, unrelated subjects was conducted in order to estimate population glutathione-S-transferases (GST) genotype frequencies in Slovak population of men and compare our results with already published data (GSEC project)^1^.
Monika Sivoňová +6 more
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Plant glutathione S-transferase classification, structure and evolution
, 2013 Glutathione S-transferases are multifunctional proteins involved in diverse intracellular events such as primary and secondary metabolisms, stress metabolism, herbicide detoxification and plant protection against ozone damages, heavy metals and ...
Moosavi, F +5 more
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Glutathione S transferase polymorphisms influence on iron overload in β-thalassemia patients
Thalassemia Reports, 2013 In patients with β-thalassemia iron overload that leads to damage to vital organs is observed. Glutathione S transferase (GST) enzymes have an antioxidant role in detoxification processes of toxic substances. This role is determined genetically.
Serena Sclafani +5 more
doaj +1 more source
Purification of glutathione S-transferase (GST) using mixed mode chromatography
, 2014 A simple and small scale laboratory method to compare between ultrasonication, glass bead shaking and chemical lysis were evaluated for the release of recombinant Glutathione S-Transferase (GST) from Escherichia coli.
Abdullah, Norhafizah, M., Sivapragasam
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Zdorovʹe Rebenka, 2014 The aim of research: to study the peculiarities of a heterogeneous airway inflammation in children with bronchial asthma (BA) under the deletion polymorphism of GSTM1 and GSTT1 genes. Materials and Methods.
O.K. Koloskova +4 more
doaj +1 more source