Results 141 to 150 of about 88,346 (287)
ChemBioChem, Accepted Article.Non‐muscle invasive bladder cancer (NMIBC) accounts for 75% of bladder cancer cases, with Bacillus Calmette‐Guérin (BCG) immunotherapy as the gold standard for high‐risk patients. BCG elicits a robust immune response but is limited by adverse effects and resistance. To enhance its efficacy, we developed a trehalose‐based conjugation strategy, tethering
Michael Grimmeisen +10 more
wiley +1 more source
The activity of antioxidant enzymes in chronic obstructive pulmonary disease in combination with comorbid obesity [PDF]
, 2013 Background. Chronic obstructive pulmonary disease (COPD) is one of the most common diseases in the world, whose mortality continues to increase. The focus of modern medical science and public health is obesity too, because the number of patients are ...
Fediv, O.I., Stupnytska, G.Y.
core
Mapping transcriptomic profiles of seminal vesiculitis and experimental verification
Asian Journal of UrologyObjective: Seminal vesiculitis is a prevalent infectious disease in the genitourinary system, but its intrinsic pathogenesis and molecular features remain unclear. Methods: In this study, we utilized a next-generation sequencing technology to demonstrate
Chenkui Miao +5 more
doaj
Positive correlation exists between glutathione S-transferase activity and aflatoxin formation in Aspergillus flavus [PDF]
, 1988 Manju Saxena +2 more
openalex +1 more source
ChemCatChem, EarlyView.A study of crystallographic complexes obtained from vanadium haloperoxidase enzymes can determine key amino acids, leucine, and phenylalanine, that change their structural orientation to allow either chloride or bromide to bind to the enzymes active site, thereby determining halide specificity.
Daniel E. Mitchell +3 more
wiley +1 more source
NRF2 signalling in cytoprotection and metabolism
British Journal of Pharmacology, EarlyView., 2023 The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami +4 more
wiley +1 more source
Reversible Activation of Rat Liver Microsomal Glutathione S-Transferase Activity by 5,5'-Dithiobis(2-nitrobenzoic acid) and 2,2'-Dipyridyl Disulfide. [PDF]
, 1980 Ralf Morgenstern +5 more
openalex +1 more source
Cytoskeleton, EarlyView.ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro +5 more
wiley +1 more source
The development of glutathione S-transferase subunits in rat liver. Sensitive detection of the major subunit forms of rat glutathione S-transferase by using an e.l.i.s.a. method [PDF]
, 1989 FIONA M. McCUSKER +2 more
openalex +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Busulfan is administered intravenously in conditioning regimens prior to allogeneic hematopoietic stem cell transplantation (HSCT), with model‐informed precision dosing (MIPD) targeting a 4‐day cumulative AUC of 80–100 mg*hour/L. Three pharmacokinetic (PK) models—Bognar, Langenhorst, and McCune—were evaluated using data with a minimum of 1 and a median
Rashudy F. Mahomedradja +13 more
wiley +1 more source