Results 151 to 160 of about 88,346 (287)

Mechanism for the several activities of the glutathione S-transferases.

, 1976
James H. Keen, W H Habig, William B. Jakoby   +2 more
openalex   +1 more source

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

European Journal of Organic Chemistry, Volume 28, Issue 23, June 23, 2025.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source

The Chicken Egg Genotoxicity Assay (CEGA): Assessing Target Tissue Exposure and Metabolism in the Embryo‐Fetal Chicken Livers

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The Chicken Egg Genotoxicity Assay (CEGA) is an avian egg‐based model that utilizes the livers of developing chicken embryo‐fetuses to assess the ability of chemicals to produce direct DNA damage. The main goal of the study was to evaluate target tissue exposure and metabolism in the CEGA to assess its suitability as a biologically relevant ...
Yax Thakkar, T. Kobets, Anne Marie Api, J. D. Duan, G. M. Williams   +4 more
wiley   +1 more source

The Role of Arginase and some Parameters in Diabetic Type 2 Patients with and without Retinopathy

مجلة كلية الطب
Background: Oxidative stress plays a major role in the pathogenesis of diabetes mellitus by damaging cellular organelles and enzymes in blood such as arginase1, insulin and glutathione s-transferase; increasing lipid peroxidation such as malondialdehyde
Maha F. Yassen, Fayhaa. M. Khaleel
doaj   +1 more source

Glutathione-S-Epoxide Transferase In Mouse Skin And Human Foreskin

, 1976
Hasan Mukhtar, Edward Bresnick
openalex   +1 more source

Selective elution of rodent glutathione S-transferases and glyoxalase I from the S-hexyglutathione-Sepharose affinity matrix [PDF]

, 1988
John D. Hayes
openalex   +1 more source

The purification and properties of glutathione S-transferase from Ditylenchus myceliophagus [PDF]

, 1997
L'activité de la glutathion S-tranférase cytoplasmique chez #Dytylenchus myceliophagus$ a été attribuée à quatre isoenzymes, DmI, DmII, DmIII et DmIV, par combinaison de la chromatographie focalisante et de la chromatographie d'affinité au moyen de l ...
Barrett, J., Perry, R.N., Persaud, A.D.
core  

Glutathione S-transferases of rat liver active on organophosphorus triesters.

, 1977
Kenji Usui, Takashi Shishido, Jun-ichi FUKAMI   +2 more
openalex   +2 more sources

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Enhanced Expression of Glutathione S-Transferase in the Hippocampus Following Acute Treatment With Trimethyltin In Vivo

Journal of Pharmacological Sciences, 2010
We investigated the effects of treatment with trimethyltin (TMT) on the expression of glutathione-related enzymes in mouse hippocampus. TMT promoted the expression of glutathione S-transferase (GST) Ya/Yc mRNA, and GSTA2 protein, but not that of ...
Reiko Nagashima, Shohei Sano, Nguyen Quynh Huong, Tatsuo Shiba, Kiyokazu Ogita   +4 more
doaj