Results 241 to 250 of about 986,817 (390)

Integration of Serum and Liver Metabolomics with Antioxidant Biomarkers Elucidates Dietary Energy Modulation of the Fatty Acid Profile in Donkey Meat. [PDF]

Antioxidants (Basel)
Li L, Zhao Y, Guo Y, Shi B, Zhang J, Meng F, Hui F, Zhang Q, Guo X, Yan S.   +9 more
europepmc   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

Impact of oxidative stress on female reproductive parameters: an analysis of systemic and follicular biomarkers. [PDF]

JBRA Assist Reprod
Rodrigues AQ, Carvalho GG, Piau TB, Veiga FH, Souza PEN, Moreira DC, Tierno NIZ, Macedo YA, Amaral MEB, Nakagawa HM, Goulart JT, Paulini F.   +11 more
europepmc   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Astragaloside IV ameliorates atrazine-induced male reproductive toxicity: an <i>in vivo</i> and <i>in silico</i> analysis. [PDF]

Front Toxicol
Sirasanagandla SR, Al Mushaiqri M, Al-Majrafi F, Al-Abri N, Jayaraman S, Al Huseini IS.   +5 more
europepmc   +1 more source

Zinc binding ligands and cellular zinc trafficking: Apo-metallothionein, glutathione, TPEN, proteomic zinc, and Zn-Sp1

, 2007
Ujala Rana, Rajendra K. Kothinti, Jeffrey W. Meeusen, Niloofar M. Tabatabai, Susan Krezoski, David H. Petering   +5 more
openalex   +1 more source

Increased loss and decreased synthesis of hepatic glutathione after acute ethanol administration. Turnover studies [PDF]

, 1985
Hernán Speisky, Angus W. MacDonald, Gregory I. Giles, H Orrego, Yedy Israel   +4 more
openalex   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

Advanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao, Qian Hao, Yu Gan, Jing Tong, Xiaodan Chen, Shuran Tan, Ruiwen Ruan, Yingdan Huang, Mingming Cao, Jun Deng, Tao Han, Getao Shi, Bo Gao, Yu Zhang, Xiang Zhou   +14 more
wiley   +1 more source

Magnesium deficiency and high light intensity enhance activities of superoxide dismutase, ascorbate peroxidase, and glutathione reductase in bean leaves.

Plant Physiology, 1992
I. Cakmak, H. Marschner
semanticscholar   +1 more source

Discrimination of homocysteine, cysteine and glutathione using an aggregation-induced-emission-active hemicyanine dye

, 2014
Sijie Chen, Yuning Hong, Jianzhao Liu, Nai‐Wen Tseng, Liu Yang, Engui Zhao, Jacky W. Y. Lam, Ben Zhong Tang   +7 more
openalex   +2 more sources