Antioxidants, 2022 Proteins in the thioredoxin superfamily share a similar fold, contain a -CXXC- active site, and catalyze oxidoreductase reactions by dithiol-disulfide exchange mechanisms. Protein disulfide isomerase (PDI) has two -CGHC- active sites.
Mirva J. Saaranen +6 more
doaj +1 more source
Evaluation of oxidative stress biomarkers for differentiating bacterial and viral infections: a comparative study of glutathione disulfide (GSSG) and reduced glutathione (GSH). [PDF]
Med Pharm RepMilhelm Z +8 more
europepmc +2 more sources
Environmentally friendly recycling system for epoxy resin with dynamic covalent bonding
Science and Technology of Advanced Materials, 2021 Recycling of epoxy resin and its composites is extremely difficult due to its thermoset nature. In this study, we proposed the environmentally-friendly recycling system of epoxy resin with dynamic covalent bonding in the assistance of cysteine-containing
Hsing-Ying Tsai +3 more
doaj +1 more source
A redox-responsive hyaluronic acid-based hydrogel for chronic wound management [PDF]
, 2021 Polymer-based hydrogels have been widely applied for chronic wound therapeutics, due to their well-acclaimed wound exudate management capability. At the same time, there is still an unmet clinical need for simple wound diagnostic tools to assist clinical decision-making at the point of care and deliver on the vision of patient-personalised wound ...
arxiv +1 more source
Thiol-disulfide metabolism in kidney tissue at the administration of some copper coordination compounds [PDF]
The Moldovan Medical Journal, 2020 Background: Thiol-disulfide metabolism is essential for normal function of the organism. Thus the interest of the scientists in this area of research continues to grow.
Veronica Sardari +7 more
doaj +1 more source
Band structure of molybdenum disulfide: from first principle to analytical band model [PDF]
J. Comput. Electron. 21, 571-581 (2022), 2022 A simple band model such as the effective mass approximation (EMA) can be used to quickly obtain the lower-energy region for the band structure of monolayer molybdenum disulfide. But the EMA band model cannot give the correct description for the band structure in the higher-energy region.
arxiv +1 more source
The dithiol mechanism of class I glutaredoxins promotes specificity for glutathione as a reducing agent. [PDF]
Redox BiolClass I glutaredoxins reversibly reduce glutathione- and nonglutathione disulfides with the help of reduced glutathione (GSH) using either a monothiol mechanism or a dithiol mechanism.
Lang L, Reinert P, Diaz C, Deponte M.
europepmc +2 more sources
Glutathione cycle in diquat neurotoxicity: Assessed by intrastriatal pre-treatment with glutathione reductase [PDF]
Acta Veterinaria, 2013 Diquat (DQ) neurotoxicity mechanisms are unknown, although, it's systemic toxicity is mediated by free radical reactions. The role of glutathione cycle was assessed by glutathione reductase (GR) applied in the pre-treatment of DQ poisoning.
Đurđević Dragan +5 more
doaj +1 more source
Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog [PDF]
, 2021 Sulfur mustard (SM), a chemical warfare agent, is a strong alkylating compound that readily reacts with numerous biomolecules. The goal of the present work was to define and validate new biomarkers of exposure to SM that could be easily accessible in urine or plasma. Because investigations using SM are prohibited by the Organization for the Prohibition
arxiv +1 more source
An Orally Bioavailable (Mice) Prodrug of Glutathione
Antioxidants, 2021 L-Cysteine-glutathione mixed disulfide (CySSG), a prodrug of glutathione (GSH), was found to be orally bioavailable in mice, and protected mice against a toxic dose of acetaminophen.
Daune L. Crankshaw +3 more
doaj +1 more source