Results 31 to 40 of about 48,461 (279)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Objective: to study the features of metabolism of nitric oxide and thiol-disulfide balance parameters in patients with psoriasis combined with essential hypertension. Materials and metods.
G. I. Makurina
doaj +1 more source
Effect of Prolonged High-Fat Diet on Thiol-Disulfide Homeostasis in Rats [PDF]
International Journal of Biomedicine, 2013 The aim of this study was to determine the effect of a prolonged high-fat (HF) on thiol-disulfide homeostasis via the activity of the glutathione redox-system (GRS) in rat blood and liver. Methods: The experiment was conducted on male Wistar rats.
Tatyana P. Novgorodtseva +1 more
doaj
Mitochondrial thiol-disulfide system under acute hypoxia and hypoxic-hyperoxic adaptation [PDF]
The Ukrainian Biochemical Journal, 2014 The authors investigated the state of mitochondrial glutathione pool (reduced and oxidized glutathione, protein-GSH mixed disulfides), content of carbonyl groups and free sulfhydryl groups of proteins, protein expression of key mitochondrial antioxidant ...
O. A. Gonchar, I. N. Mankovska
doaj +1 more source
BiomoleculesThe oxidation of cysteines in crystallins is a major age-related modification associated with cataract formation. The purpose of this research was to determine the susceptibility of γS-crystallin to glutathionylation-induced oxidation and disulfide bond ...
Kate Halverson-Kolkind +5 more
doaj +1 more source
Redox BiologyClass I glutaredoxins reversibly reduce glutathione- and nonglutathione disulfides with the help of reduced glutathione (GSH) using either a monothiol mechanism or a dithiol mechanism.
Lukas Lang +3 more
doaj +1 more source
Patologìâ, 2019 Objective. To determine in an experimental study the nature of changes in the status of the thiol-disulfide system of rats with encephalopathy, due to the influence of complex of anti-tuberculosis drugs for the treatment of chemoresistant tuberculosis ...
A. V. Levich +3 more
doaj +1 more source
Epididymis response partly compensates for spermatozoa oxidative defects in snGPx4 and GPx5 double mutant mice. [PDF]
PLoS ONE, 2012 We report here that spermatozoa of mice lacking both the sperm nucleus glutathione peroxidase 4 (snGPx4) and the epididymal glutathione peroxidase 5 (GPx5) activities display sperm nucleus structural abnormalities including delayed and defective nuclear ...
Anaïs Noblanc +12 more
doaj +1 more source
Immunoproteomic to identify antigens in the intestinal mucosa of Crohn's disease patients. [PDF]
PLoS ONE, 2013 Incidences of Crohn disease (CD) have increased significantly in the last decade. Immunoproteomics are a promising method to identify biomarkers of different diseases. In the present study, we used immunoproteomics to study proteins of intestinal mucosal
Zheng Zhou +6 more
doaj +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Assessment of thiol-disulfide and glutathione homeostasis after levothyroxine replacement in individuals with autoimmune or nonautoimmune hypothyroidism [PDF]
Archives of Endocrinology and MetabolismObjective Thyroid hormones are known to affect the biosynthesis and degradation of antioxidant compounds, suggesting a possible link between hypothyroidism and oxidative stress.
Almila Senat +4 more
doaj +1 more source