Results 1 to 10 of about 275,416 (288)

Potential role and therapeutic implications of glutathione peroxidase 4 in the treatment of Alzheimer's disease. [PDF]

open access: yesNeural Regen Res
Alzheimer’s disease is an age-related neurodegenerative disorder with a complex and incompletely understood pathogenesis. Despite extensive research, a cure for Alzheimer’s disease has not yet been found.
Shen Y   +6 more
europepmc   +2 more sources

Diabetic Retinopathy and Regulation of Mitochondrial Glutathione-Glutathione Peroxidase Axis in Hyperhomocysteinemia. [PDF]

open access: yesAntioxidants (Basel)
Diabetic patients have elevated homocysteine levels, and hyperhomocysteinemia is shown to exacerbate mitochondrial damage, which plays a central role in diabetic retinopathy. Glutathione peroxidases (GPx) catalyze hydrogen peroxide (H2O2) reduction using
Malaviya P, Kowluru RA.
europepmc   +2 more sources

Long-term results of the enzyme glutation system activity in experimental ovarian cancer

open access: yesJournal of Education, Health and Sport, 2022
The article presents the experimental results of the investigation the glutathione system activity (glutathione peroxidase and glutathione reductase) in rats simulated ovarian ascites tumor.
L. Yershova   +4 more
doaj   +1 more source

Role of Serum Vitamin B12 and Glutathione Peroxidase during Third Trimester of Pregnancy with Gestational Diabetes Mellitus

open access: yesPakistan Armed Forces Medical Journal, 2023
Objective: To investigate the role and relationship of serum Vitamin B12 and Glutathione peroxidase in pregnancy with gestational diabetes mellitus (GDM). Study Design: Comparative cross-sectional study.
Aasia Kanwal   +3 more
doaj   +1 more source

Glutathione Peroxidase 4 as a Therapeutic Target for Anti-Colorectal Cancer Drug-Tolerant Persister Cells

open access: yesFrontiers in Oncology, 2022
BackgroundDespite the effectiveness of chemotherapy and targeted therapy for colorectal cancer, drug resistance drives therapy failure and tumor relapse.
Xiaoli Zhang   +8 more
doaj   +1 more source

Anti-cancer effect of thiacremonone through down regulation of peroxiredoxin 6. [PDF]

open access: yesPLoS ONE, 2014
Thiacremonone (2, 4-dihydroxy-2, 5-dimethyl-thiophene-3-one) is an antioxidant substance as a novel sulfur compound generated from High-Temperature-High-Pressure-treated garlic.
Miran Jo   +15 more
doaj   +1 more source

COMPARISON OF LEVELS OF NITRIC OXIDE, SUPEROXIDE DISMUTASE AND GLUTATHIONE PEROXIDASE OF GASTRIC JUICE IN INFECTED AND NON-INFECTED PATIENTS WITH HELICOBACTER PYLORI [PDF]

open access: yesActa Medica Iranica, 2006
Helicobacter Pylori infection leads to different clinical and pathological outcomes in humans, including chronic gastritis and gastric neoplasia. It has been demonstrated that oxidative stress associated with inflammation plays an important role in ...
M. Ansari   +4 more
doaj   +2 more sources

Decreased Glutathione Peroxidase Activities with Concomitant Increased Oxidized Glutathione Levels among Residents in an Arsenic Contaminated Community of Southern Thailand

open access: yesWalailak Journal of Science and Technology, 2011
Glutathione peroxidase (GPx) and glutathione are important antioxidants responsible for the scavenging of reactive oxygen species (ROS). It has been shown that changes in GPx activities and glutathione levels are associated with various diseases ...
Warangkana CHUNGLOK
doaj   +1 more source

GPX2 overexpression indicates poor prognosis in patients with hepatocellular carcinoma

open access: yesTumor Biology, 2017
Glutathione peroxidase 2 has important role of tumor progression in lots of carcinomas, yet little is known about the prognosis of glutathione peroxidase 2 in hepatocellular carcinoma.
Ting Liu   +10 more
doaj   +1 more source

Effect of Selenium on Hatchability and Cellular Glutathione Peroxidase mRNA Expression during Embryogenesis in Japanese Quail (Coturnix japonica)

open access: yesThe Journal of Poultry Science, 2009
Cellular glutathione peroxidase has important antioxidant and detoxification functions by protecting cells from oxidative damage induced by reactive oxygen species.
Sopon Wilaison, Makoto Mori
doaj   +1 more source

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