Results 131 to 140 of about 508,182 (337)

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source

1H, 13C, and 15N assignment of the oxidized and reduced forms of T. brucei glutathione peroxidase-type tryparedoxin peroxidase [PDF]

, 2008
Johannes Melchers, Luise Krauth‐Siegel, Claudia Muhle‐Goll   +2 more
openalex   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Erythrocyte Selenium-Glutathione Peroxidase Activity Is Lower in Patients with Coronary Atherosclerosis.

, 1997
A. Yeĝin, Haluk YEGIN, Yakup Alıcıgüzel, Necmi Değer, Ender Semiz   +4 more
openalex   +2 more sources

Impaired Angiogenesis in Glutathione Peroxidase-1–Deficient Mice Is Associated With Endothelial Progenitor Cell Dysfunction [PDF]

, 2005
Gennaro Galasso, Stephan Schiekofer, Kaori Sato, Rei Shibata, Diane E. Handy, Noriyuki Ouchi, Jane A. Leopold, Joseph Loscalzo, Kenneth Walsh   +8 more
openalex   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Comparison of plasma malondialdehyde, glutathione, glutathione peroxidase, hydroxyproline and selenium levels in patients with vitiligo and healthy controls

Indian Journal of Dermatology, 2008
Background: The etiology and pathophysiologic mechanism of vitiligo are still unclear. The relationship between increased oxidative stress due to the accumulation of radicals and reactive oxygen species and the associated changes in blood and epidermal ...
Ozturk I, Batcioglu Kadir, Karatas Fikret, Hazneci Ersoy, Genc Metin   +4 more
doaj  

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Hydroperoxide reduction by thioredoxin‐specific glutathione peroxidase isoenzymes of Arabidopsis thaliana [PDF]

, 2006
Aqib Iqbal, Yukinori Yabuta, Toru Takeda, Yoshihisa Nakano, Shigeru Shigeoka   +4 more
openalex   +1 more source