Results 111 to 120 of about 371,704 (300)
Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs
Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley +1 more source
Advanced Science, EarlyView.PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang +5 more
wiley +1 more source
Advanced Science, EarlyView.Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu +7 more
wiley +1 more source
Advanced Science, EarlyView.Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu +12 more
wiley +1 more source
The use of soybean peroxidase in amperometric biosensors [PDF]
, 2004 Traditionally Horseradish peroxidase (HRP) the archetypal class III plant peroxidase has been investigated with respect to chemical modifications, organic solvent tolerance studies, reaction kinetics, kinetics in organic solvents, immunohistochemical and
Carolan, Neil
core +2 more sources
AntioxidantsDiabetic patients have elevated homocysteine levels, and hyperhomocysteinemia is shown to exacerbate mitochondrial damage, which plays a central role in diabetic retinopathy. Glutathione peroxidases (GPx) catalyze hydrogen peroxide (H2O2) reduction using
Pooja Malaviya, Renu A. Kowluru
doaj +1 more source
Efeitos do zinco sobre os sistemas de degradação de peróxidos de células neurais [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em BioquímicaZinco na sua forma ionica livre e mantido em concentracoes muito baixas nas celulas de mamiferos.
Souza, Luiz Felipe de
core
Glutathione peroxidase and catalase modulate the genotoxicity of arsenite
, 2010 [[abstract]]The X-ray hypersensitive Chinese hamster ovary (CHO) cells, xrs-5, are also more sensitive to sodium arsenite in terms of cell. growth and micronucleus induction than CHO-K1 cells. Since reactive oxygen species are suggested to be involved in
Wang TS;Shu YF;Liu YC;Jan KY;Huang H
core +1 more source
Advanced Science, EarlyView.In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye +9 more
wiley +1 more source
Genetics of glutathione peroxidase [PDF]
, 2003 Glutathione peroxidase is a selenoenzyme responsible for elimination of reactive oxygen species. Since its first identification in 1957 five isoforms have been typified.Several environmental factors, like feed composition, trace element status and ...
Mézes Miklós
core