Results 221 to 230 of about 167,749 (264)
Some of the next articles are maybe not open access.
Glutathione peroxidase and oxidative stress
Toxicology Letters, 1995In this study, overexpression of the cDNA for the major cytoplasmic glutathione peroxidase isoenzyme, GSH Peroxidase 1 (GSHPx-1), in human MCF-7 breast cancer cells has been shown to significantly increase the tolerance of these cells to oxidative stress produced by hydrogen peroxide or by the redox cycling of the quinone-containing anticancer agent ...
openaire +2 more sources
Phylogenetic distribution of glutathione peroxidase
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 19791. The enzyme glutathione peroxidase (E.C.1.11.1.9), known to be a selenoprotein from mammalian sources, was detected in the following vertebrates: fish, frog, salamander, and turtle. 2. Among invertebrates, the enzyme was detected in crayfish and snail but not in insects or earthworm. 3.
J, Smith, A, Shrift
openaire +2 more sources
A pseudogene for human glutathione peroxidase
Gene, 1992Glutathione peroxidases (GPx) serve a bioprotective function in the reduction of peroxides to less toxic substances. Both cellular and secreted forms of the protein have been reported, as well a number of distinct cDNA sequences. Previous efforts have described three distinct loci on human chromosomes 3, 21 and X which hybridize to a GPX cDNA and these
A M, Diamond +3 more
openaire +2 more sources
The Role of Glutathione Peroxidases in Trypanosomatids
Biological Chemistry, 2003Reactive oxygen species are the unwanted by-products of aerobic metabolism. To protect cells against their potentially lethal effects a series of pathways have evolved that are collectively called the oxidative defence system. In most eukaryotes, catalases and selenium-dependent glutathione peroxidases form the front line of defence against ...
Shane R, Wilkinson, John M, Kelly
openaire +2 more sources
Inactivation of Glutathione Peroxidase by Benzaldehyde
Toxicology and Applied Pharmacology, 1996Chronic benzaldehyde exposure is known to cause central nervous system (CNS) disturbances. Previous studies have shown that benzaldehyde causes the formation of reactive oxygen species (ROS) in rat synaptosomal fractions. Benzaldehyde has also been implicated in ROS formation in the CNS of rats treated with toluene.
T, Tabatabaie, R A, Floyd
openaire +2 more sources
Glutathione Peroxidase 4 and Ferroptosis
2016Glutathione peroxidase 4 (Gpx4) is one of eight members of the mammalian glutathione peroxidase family of enzymes. Gpx4 is unique due to its capacity to efficiently reduce phospholipid hydroperoxides. Additionally, it has been recognized that Gpx4 governs a novel form of non-apoptotic cell death, named ferroptosis.
Friedmann Angeli, J.P.F. +2 more
openaire +2 more sources
Research progress of glutathione peroxidase family (GPX) in redoxidation
Frontiers in Pharmacology, 2023Wei Guanghui, Hua Yi, Pei Jun
exaly