Results 231 to 240 of about 371,704 (300)

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Glutathione Peroxidase-Like Activity of Functionalized Tellurides: Insights into the Oxidation Mechanism Through Activation Strain Analysis. [PDF]

Inorg Chem
Rubbi A, Tanini D, Capperucci A, Orian L.   +3 more
europepmc   +1 more source

Glutathione peroxidase 7 knockdown inhibits growth, invasion, and migration while enhancing oxidative stress and ferroptosis in osteosarcoma cells. [PDF]

J Bone Oncol
He R, Xiao X, Tang X, Lv C.
europepmc   +1 more source

Curcumin nanocrystals ameliorate ferroptosis of diabetic nephropathy through glutathione peroxidase 4. [PDF]

Front Pharmacol
Xue M, Tian Y, Zhang H, Dai S, Wu Y, Jin J, Chen J.   +6 more
europepmc   +1 more source

The role of glutathione peroxidase 4 in the progression, drug resistance, and targeted therapy of non-small cell lung cancer. [PDF]

Oncol Res
Wei J, Zhu L.
europepmc   +1 more source

The Manifestation of the Dual ROS-Processing and Redox Signaling Roles of Glutathione Peroxidase-like Enzymes in Development of <i>Arabidopsis</i> Seedlings. [PDF]

Antioxidants (Basel)
Bela K, Tompa B, Riyazuddin R, Horváth E, Jász K, Hajnal Á, Bangash SAK, Gallé Á, Csiszár J.   +8 more
europepmc   +1 more source

Glutathione peroxidase 4 overexpression induces anomalous subdiffusion and impairs glioblastoma cell growth. [PDF]

J Biol Eng
Teferi N, Ekanayake A, Owusu SB, Moninger TO, Sarkaria JN, Tivanski AV, Petronek MS.   +6 more
europepmc   +1 more source

Glutathione Peroxidase 4

, 2016
Glutathione peroxidase 4 (GPx4) is a selenocysteine (Sec)-containing glutathione peroxidase. GPx4 catalyzes the reduction of hydroperoxides and the oxidation of thiols through a ping-pong mechanism in which the redox transitions are faster than the formation of enzyme-substrate complexes; thus, K m and V max are infi nite.
MAIORINO, MATILDE, BOSELLO TRAVAIN, VALENTINA, COZZA, GIORGIO, MIOTTO, GIOVANNI, ORIAN, LAURA, ROVERI, ANTONELLA, TOPPO, STEFANO, ZACCARIN, MATTIA, URSINI, FULVIO   +8 more
openaire   +3 more sources

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Glutathione peroxidases

Biochimica et Biophysica Acta (BBA) - General Subjects, 2013
With increasing evidence that hydroperoxides are not only toxic but rather exert essential physiological functions, also hydroperoxide removing enzymes have to be re-viewed. In mammals, the peroxidases inter alia comprise the 8 glutathione peroxidases (GPx1-GPx8) so far identified.Since GPxs have recently been reviewed under various aspects, we here ...
Brigelius Flohé R, MAIORINO, MATILDE
openaire   +2 more sources