Results 251 to 260 of about 122,606 (315)
Exploration, EarlyView.Self‐assembled S‐Cu(I)‐S sites were spatially isolated onto a two‐dimensional Ti3C2 surface to produce a structurally well‐defined and highly functional single‐site copper(I) nanomodulator CuNTD, which can induce severe immunogenic cell death through multiple regulatory pathways of synergistic cascade photothermal‐amplified ROS storms, cuproptosis and ...
Yuanyuan Zhang +11 more
wiley +1 more source
Exploration, EarlyView.Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang +4 more
wiley +1 more source
Tumor Diagnosis and Treatment Based on Stimuli‐Responsive Aggregation of Gold Nanoparticles
Exploration, EarlyView.This review summarizes the current strategies for inducing gold nanoparticles aggregation and its advances in tumor diagnosis and treatment. The authors hope this review can provide a valuable reference for the further development of AuNPs clinical applications.
Xiaowei Chang, Huaiyu Wang, Xin Chen
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Exploration, EarlyView.Targeting mitochondrial dysfunction presents a potential therapeutic approach for treating spinal cord injury. We have successfully designed and synthesized a functional Se@NADH nanodrug system. This system offers neuroprotective and neuroregenerative benefits by modulating mitochondrial function and neutralizing reactive oxygen species, thereby ...
Guibin Gao +12 more
wiley +1 more source
Berries: Health Effects via Modulation of the Gut Microbiota
Food Frontiers, EarlyView.ABSTRACT Berries are widely regarded as beneficial foods, rich in polyphenols, flavonoids, and other bioactive compounds that could positively influence human health. Although the gut microbiota plays a crucial role in metabolism and physiology of humans, the interaction between berries and human gut microbiota activity remains unclear.
Manjin Xu +11 more
wiley +1 more source
Food Frontiers, EarlyView.Lipopolysaccharide‐induced oxidative stress results in intestine injury. The prophylactic oral anthocyanin and its fecal bacteria suspension can ameliorate the damage through the Lactococcus and metabolites, which lead to modulation of antioxidant‐ and inflammation‐related signaling pathways such as NF‐κB and Nrf2/Keap1, which in turn improves ...
Pingfei Qiu +9 more
wiley +1 more source
Food Frontiers, EarlyView.Olive leaf (OL) extracts were assessed for biomedical and phytochemical profiles. High‐OL extract was the most effective in inhibiting AChE, COX‐2, and iron‐reducing activity. Low‐ and high‐OL extracts showed significant effects against Aβ and tau toxicity in vivo. All extracts modulated redox biology at different levels. Only high‐OL extract prevented
Jose M. Romero‐Marquez +12 more
wiley +1 more source