Results 21 to 30 of about 487,455 (339)

Effect of Selenium on Hatchability and Cellular Glutathione Peroxidase mRNA Expression during Embryogenesis in Japanese Quail (Coturnix japonica)

open access: yesThe Journal of Poultry Science, 2009
Cellular glutathione peroxidase has important antioxidant and detoxification functions by protecting cells from oxidative damage induced by reactive oxygen species.
Sopon Wilaison, Makoto Mori
doaj   +1 more source

Glutathione peroxidases as oncotargets

open access: yesOncotarget, 2017
Oxidative stress is a disturbance in the equilibrium among free radicals, reactive oxygen species, and endogenous antioxidant defense mechanisms. Oxidative stress is a result of imbalance between the production of reactive oxygen and the biological system's ability to detoxify the reactive intermediates or to repair the resulting damage.
Yang Jiao   +3 more
openaire   +4 more sources

Properties and Regulation of Glutathione Peroxidase [PDF]

open access: yesJournal of Biological Chemistry, 1970
Abstract GSH peroxidase has been purified approximately 2500-fold from pig's blood. With cumene hydroperoxide as substrate, kinetic analysis on the purified enzyme gave nonlinear Lineweaver-Burk plots for the hydroperoxide substrate. Linear Lineweaver-Burk plots were obtained for GSH and a limiting Km value of approximately 3 mm was obtained for GSH. A
K.G. Reid   +3 more
openaire   +2 more sources

Effect of ochratoxin A and buthionine sulfoximine on proteome and ascorbate-glutathione cycle enzymes in Arabidopsis thaliana

open access: yesBiologia Plantarum, 2015
In this study, proteome and activities of glutathione (GSH)-related enzymes were investigated in detached leaves of Arabidopsis thaliana treated with ochratoxin A (OTA) alone or supplemented with buthionine sulfoximine (BSO, a specific inhibitor of the ...
J. R. Hao   +8 more
doaj   +1 more source

Prognostic significance of glutathione peroxidase 2 in gastric carcinoma

open access: yesTumor Biology, 2017
Increasing evidence suggests that the glutathione peroxidase 2 may actually play important roles in tumorigenesis and progression in various human cancers such as colorectal carcinomas and lung adenocarcinomas. However, the role of glutathione peroxidase
Dongzhe Liu   +5 more
doaj   +1 more source

Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4.

open access: yesJournal of Medicinal Chemistry, 2019
Glutathione peroxidase 4 (GPX4) is essential for cell membrane repair, inflammation suppression, and ferroptosis inhibition. GPX4 upregulation provides unique drug discovery opportunities for inflammation and ferroptosis-related diseases.
Cong Li   +7 more
semanticscholar   +1 more source

Protective Effect of Wild Ginseng Extract against y-BHP-induced Oxidative Damage in HepG2 Cells Using DNA Chip

open access: yesJournal of Pharmacopuncture, 2007
Objectives : This study was carried out to examine protective effect of wild ginseng extract on HepG2 human hepatoma cell line against tert-Butyl hydroperoxide (t-BHP)-induced oxidative damage.
Hyung-Seok Kim   +2 more
doaj   +1 more source

Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats

open access: yesReproductive Biology and Endocrinology, 2009
Background The alterations of the glutathione peroxidase enzyme complex system occur in physiological conditions such as aging and oxidative stress consequent to strenuous exercise.
Martino Guglielmo, Gallo Giuseppe
doaj   +1 more source

Glutathione metabolism system under condition of transplantation of muscle tissue in rats

open access: yesRegulatory Mechanisms in Biosystems, 2015
The paper presents the results of determining the amount of reduced glutathione, glutathione reductase and glutathione peroxidase activity at transplantation of muscle tissue taken from rats from the same litter.
O. V. Kulibaba   +4 more
doaj   +1 more source

The Impact of Passive Smoking on Salivary Glutathione Peroxidase and Selenium in Relation to Dental Caries Severity among Five Years Old Children

open access: yesIndian Journal of Dental Research, 2023
Background: It had been found that passive smoking may have the same harmful effect as tobacco cigarettes smoking. Aims: This study was conducted to determine the effect of passive smoking on salivary glutathione peroxidase and selenium in relation to ...
Shahba’a Munther   +2 more
doaj   +1 more source

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