Results 51 to 60 of about 278,744 (306)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The effect of magnesium citrates on pro-oxidative/antioxidative status in rat liver at experimental diabetes

open access: yesБіологічні студії, 2016
The activity of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, the content of reduced glutathione and products of lipid peroxidation in liver tissue of rats with alloxan-indused diabetes were investigated.
O. Shatynska, R. Iskra
doaj   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

open access: yesAdvanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Catalase, glutathione peroxidase, metabolic syndrome, superoxide dismutase

open access: yesMajalah Kedokteran Bandung, 2012
Labor pain is part of a normal process, which often causes physiological and psychological stress to mother. These stress have impact to both mother and fetus. Largely (90%) labor comes with pain and in some cases severe pain.
Tarsikah   +2 more
doaj   +1 more source

Otoprotection Mechanisms Against Oxidative Stress Caused by Cisplatin

open access: yesInternational Archives of Otorhinolaryngology, 2020
Introduction Cisplatin damages the auditory system and is related to the generation of free radicals. Glutathione peroxidase is an endogenous free radicals remover.
Maiara Santos Gonçalves   +4 more
doaj   +1 more source

Differential redox state contributes to sex disparities in the response to influenza virus infection in male and female mice [PDF]

open access: yes, 2018
Influenza virus replicates intracellularly exploiting several pathways involved in the regulation of host responses. The outcome and the severity of the infection are thus strongly conditioned by multiple host factors, including age, sex, metabolic ...
Ann Maria Clemente   +17 more
core   +2 more sources

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim   +5 more
wiley   +1 more source

THE STATE OF GLUTATHIONE SYSTEM IN RAT TISSUES WITH TRAUMA MUSCULOSKELETAL SYSTEM IN THE METHIONINE INDUCED HYPERHOMOCYSTEINEMIA

open access: yesМедицинский вестник Юга России, 2015
Purpose: to research the glutathione system state in rat tissues after trauma of the musculoskeletal system in a methionineinduced hyperhomocysteinemia.Materials and methods: the level of homocysteine in the plasma of animals, as well as the amount of ...
I. A. Alliluev   +6 more
doaj   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He   +10 more
wiley   +1 more source

Fluoride Increases Superoxide Production and Impairs the Respiratory Chain in ROS 17/2.8 Osteoblastic Cells [PDF]

open access: yes, 2014
It is known that fluoride produces oxidative stress. Inflammation in bone tissue and an impairment of the respiratory chain of liver have been described in treatments with fluoride. Whether the impairment of the respiratory chain and oxidative stress are
Fina, Brenda   +3 more
core   +1 more source

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