Metabolomics analysis of children with autism, idiopathic-developmental delays, and Down syndrome. [PDF]
Although developmental delays affect learning, language, and behavior, some evidence suggests the presence of disturbances in metabolism are associated with psychiatric disorders.
Abbeduto, Leonard+3 more
core +1 more source
Developmental Changes in Hepatic Antioxidant Capacity Are Age- and Sex-Dependent
Developmental inadequacy in hepatic antioxidant defenses may contribute to chemical toxicity and pediatric liver diseases. We measured a comprehensive panel of antioxidants in liver tissue from 27 normal pediatric donors.
Shogo J. Miyagi+3 more
doaj
Glutathione reductase system changes in HTLV-1 infected patients. [PDF]
Ehtiati S+5 more
europepmc +1 more source
Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri+11 more
wiley +1 more source
Assigning function to active site residues of Schistosoma mansoni thioredoxin/glutathione reductase from analysis of transient state reductive half-reactions with variant forms of the enzyme. [PDF]
Smith MM, Moran GR.
europepmc +1 more source
ABSTRACT We examined the antioxidant and anti‐inflammatory effects of the methanolic extract of Dendranthema oreastrum (Hance) Y.Ling, commonly known as “Gu‐Jeol‐Cho” in Korea and widely found across East Asia, using an LPS‐induced acute lung injury (ALI) mouse model and TNF‐α‐stimulated NCI‐H292 cells.
Ji‐Hye Ha+11 more
wiley +1 more source
Serum levels of reduced glutathione, oxidized glutathione, and glutathione reductase activity in minor recurrent aphthous stomatitis patients. [PDF]
Zhang Z, Zhang Q, Xue Y, Fang H, Wu Z.
europepmc +1 more source
Changes in «oxidants-antioxidants» system play a significant role in the progression of disease in patients with newly diagnosed pulmonary tuberculosis in TB/HIV co-infected patients.
R.M. Yasinskyi
doaj
Purification, Characterization, and Immunological Properties for Two Isoforms of Glutathione Reductase from Eastern White Pine Needles [PDF]
James V. Anderson+2 more
openalex +1 more source
ABSTRACT Bisphenol A (BPA), an environmental toxin, exerts adverse effects by increasing mitochondrial (mROS) and intracellular (iROS) reactive oxygen species, apoptosis, and Ca2+ influx in neurological diseases. However, antioxidants can mitigate these detrimental effects. This study aimed to investigate the protective role of antioxidant alpha‐lipoic
Ramazan Çinar, Mustafa Nazıroğlu
wiley +1 more source