Results 241 to 250 of about 147,440 (362)

Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells

open access: yesCell Proliferation, EarlyView.
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai   +13 more
wiley   +1 more source

Exploring the Potential of Glutathione Reductase Overexpression to Improve Tellurium Nanoparticle Production in <i>Escherichia coli</i>. [PDF]

open access: yesInt J Mol Sci
Romero JO   +5 more
europepmc   +1 more source

Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice. [PDF]

open access: yesRedox Biol, 2021
Robbins ME   +8 more
europepmc   +1 more source

Crystals of human erythrocyte glutathione reductase

open access: yesFEBS Letters, 1975
Schulz, G.   +3 more
openaire   +4 more sources

Revitalising Aging Oocytes: Echinacoside Restores Mitochondrial Function and Cellular Homeostasis Through Targeting GJA1/SIRT1 Pathway

open access: yesCell Proliferation, EarlyView.
ECH protects senescent oocytes by stabilising the cytoskeleton, restoring mitochondrial function, reducing oxidative stress and maintaining cellular homeostasis, primarily through the GJA1/SIRT1 signalling pathway. ABSTRACT As maternal age increases, the decline in oocyte quality emerges as a critical factor contributing to reduced reproductive ...
Liuqing Yang   +13 more
wiley   +1 more source

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