Plasmodium spp. membrane glutathione S-transferases: detoxification units and drug targets
Microbial Cell, 2014 Membrane glutathione S-transferases from the class of membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG) form a superfamily of detoxification enzymes that catalyze the conjugation of reduced glutathione (GSH) to a broad ...
Andreas Martin Lisewski
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Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility? [PDF]
Redox Biology, 2021 Our lungs are exposed daily to airborne pollutants, particulate matter, pathogens as well as lung allergens and irritants. Exposure to these substances can lead to inflammatory responses and may induce endogenous oxidant production, which can cause ...
Cheryl van de Wetering +9 more
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Biological significance of glutathione S-transferases in human sperm cells
Journal of Human Reproductive Sciences, 2019 Background: Oxidative stress is considered as one of the causes of male subfertility or infertility. Among antioxidant enzymes, the crucial role belongs to glutathione S-transferases (GSTs).
Roman V Fafula +6 more
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Investigating the Potential Involvement of Glutathione S-Transferases in Defence Against Powdery Scab in Potato. [PDF]
J Fungi (Basel)Glutathione S-transferases (GSTs) are key enzymes in plant defences involved in detoxification, redox regulation, and the modulation of secondary metabolism, playing essential roles in the response to pathogen infections.
Balotf S, Wilson R, Wilson C.
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Glutathione-S-Transferases as Potential Targets for Modulation of Nitric Oxide-Mediated Vasodilation. [PDF]
Biomolecules, 2022 Glutathione-S-transferases (GSTs) are highly promiscuous in terms of their interactions with multiple proteins, leading to various functions. In addition to their classical detoxification roles with multi-drug resistance-related protein-1 (MRP1), more ...
Russell TM, Richardson DR.
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Glutathione S-Transferases in Marine Copepods
Journal of Marine Science and Engineering, 2021 The glutathione S-transferase (GST) is a complex family of phase II detoxification enzymes, known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to a wide variety of endogenous and exogenous electrophilic compounds
Chiara Lauritano +2 more
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The Glutathione System: A Journey from Cyanobacteria to Higher Eukaryotes
Antioxidants, 2023 From bacteria to plants and humans, the glutathione system plays a pleiotropic role in cell defense against metabolic, oxidative and metal stresses. Glutathione (GSH), the γ-L-glutamyl-L-cysteinyl-glycine nucleophile tri-peptide, is the central player of
Corinne Cassier-Chauvat +4 more
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The Isolation and Identification of Anthocyanin-Related GSTs in Chrysanthemum
Horticulturae, 2021 Anthocyanin is the crucial pigment for the coloration of red chrysanthemum flowers, which synthesizes in the cytosol and is transported to the vacuole for stable storage.
Yajing Li +4 more
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Glutathione and glutathione S-transferases in Barrett's epithelium [PDF]
British Journal of Cancer, 1993 Glutathione content, enzyme activity and isoenzyme composition of glutathione S-transferases were assayed in normal and Barrett's esophageal epithelium of ten patients with Barrett's esophagus. In addition, gastric and duodenal specimens from the same patients were also investigated.
W H, Peters +4 more
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Frontiers in Genetics, 2022 The plant glutathione S-transferases (GSTs) are versatile proteins encoded by several genes and play vital roles in responding to various physiological processes. Members of plant GSTs have been identified in several species, but few studies on cucumber (
Xiaoyu Duan +6 more
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