Glutathione S-Transferases in Cancer [PDF]
Antioxidants, 2021 In humans, the glutathione S-transferases (GST) protein family is composed of seven members that present remarkable structural similarity and some degree of overlapping functionalities.
Rahul Raj Singh, Katie M. Reindl
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The Multifaceted Role of Glutathione S-Transferases in Health and Disease [PDF]
Biomolecules, 2023 In humans, the cytosolic glutathione S-transferase (GST) family of proteins is encoded by 16 genes presented in seven different classes. GSTs exhibit remarkable structural similarity with some overlapping functionalities. As a primary function, GSTs play
Aslam M. A. Mazari +5 more
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Functional and Structural Diversity of Insect Glutathione S-transferases in Xenobiotic Adaptation. [PDF]
Int J Biol Sci, 2022 As a superfamily of multifunctional enzymes that is mainly associated with xenobiotic adaptation, glutathione S-transferases (GSTs) facilitate insects' survival under chemical stresses in their environment.
Koirala B K S, Moural T, Zhu F.
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The role of glutathione S-transferases in human disease pathogenesis and their current inhibitors. [PDF]
Genes DisGlutathione S-transferases (GSTs) are a family of enzymes detoxifying various harmful compounds by conjugating them with glutathione. While primarily beneficial, dysregulation of GST activity or specific isoforms can contribute to disease pathogenesis ...
Alnasser SM.
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Glutathione S-transferases in pediatric cancer [PDF]
Frontiers in Oncology, 2011 The glutathione S-transferases (GSTs) are a family of ubiquitously-expressed polymorphic enzymes important for detoxifying endogenous and exogenous compounds.
Wen eLuo +3 more
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Glutathione S-transferases Control astrocyte activation and neuronal health during neuroinflammation [PDF]
Frontiers in Molecular Biosciences, 2023 Glutathione S-transferases (GST) are phase II detoxification enzymes of xenobiotic metabolism and readily expressed in the brain. Nevertheless, the current knowledge about their roles in the brain is limited.
Ken Matoba +5 more
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Characterization of the Glutathione S-Transferases Involved in Styrene Degradation in Gordonia rubripertincta CWB2 [PDF]
Microbiology Spectrum, 2021 The glutathione S-transferases carried on the plasmid for the styrene-specific degradation pathway in the Actinobacterium Gordonia rubripertincta CWB2 were heterologously expressed in Escherichia coli.
Anna C. Lienkamp +4 more
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Efficient Adsorption and Extraction of Glutathione S-Transferases with Glutathione-Functionalized Graphene Oxide–Polyhedral Oligomeric Silsesquioxane Composite [PDF]
Molecules, 2023 Glutathione S-transferases (GSTs) are important type-II detoxification enzymes that protect DNA and proteins from damage and are often used as protein tags for the expression of fusion proteins.
Jingqi Sun, Limin Jia, Xuwei Chen
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Arabidopsis Glutathione-S-Transferases GSTF11 and GSTU20 Function in Aliphatic Glucosinolate Biosynthesis [PDF]
Frontiers in Plant Science, 2022 Glutathione (GSH) conjugation with intermediates is required for the biosynthesis of glucosinolate (GSL) by serving as a sulfur supply. Glutathione-S-transferases (GSTs) primarily work on GSH conjugation, suggesting their involvement in GSL metabolism ...
Aiqin Zhang +6 more
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Diversity of Glutathione S-Transferases (GSTs) in Cyanobacteria with Reference to Their Structures, Substrate Recognition and Catalytic Functions [PDF]
Microorganisms, 2020 Glutathione S-Transferases (GSTs) comprise a diverse group of protein superfamily involved in cellular detoxification of various harmful xenobiotics and endobiotics.
Mohandass ShylajaNaciyar +6 more
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