Results 31 to 40 of about 61,356 (195)

Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast. [PDF]

PLoS ONE, 2018
Heavy metal and metalloid contaminations are among the most concerning types of pollutant in the environment. Consequently, it is important to investigate the molecular mechanisms of cellular responses and detoxification pathways for these compounds in ...
Houman Moteshareie, Maryam Hajikarimlou, Alex Mulet Indrayanti, Daniel Burnside, Ana Paula Dias, Clara Lettl, Duale Ahmed, Katayoun Omidi, Tom Kazmirchuk, Nathalie Puchacz, Narges Zare, Sarah Takallou, Thet Naing, Raúl Bonne Hernández, William G Willmore, Mohan Babu, Bruce McKay, Bahram Samanfar, Martin Holcik, Ashkan Golshani   +19 more
doaj   +1 more source

GSTP1 and GSTM3 Variant Alleles Affect Susceptibility and Severity of COVID-19

Frontiers in Molecular Biosciences, 2021
Based on the premise that oxidative stress plays an important role in severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection, we speculated that variations in the antioxidant activities of different members of the glutathione S-transferase ...
Vesna Coric, Vesna Coric, Ivana Milosevic, Ivana Milosevic, Tatjana Djukic, Tatjana Djukic, Zoran Bukumiric, Zoran Bukumiric, Ana Savic-Radojevic, Ana Savic-Radojevic, Marija Matic, Marija Matic, Djurdja Jerotic, Djurdja Jerotic, Nevena Todorovic, Milika Asanin, Milika Asanin, Marko Ercegovac, Marko Ercegovac, Jovan Ranin, Jovan Ranin, Goran Stevanovic, Goran Stevanovic, Marija Pljesa-Ercegovac, Marija Pljesa-Ercegovac, Tatjana Simic, Tatjana Simic, Tatjana Simic   +27 more
doaj   +1 more source

Genetic polymorphisms of glutathione S transferase and cervical intraepithelial neoplasia

Romanian Journal of Laboratory Medicine, 2016
Aim: The present study aim to analyze the relationship between GST M/T genotypes of glutathione S-transferases and cervical intraepithelial neoplasia.
Daniel Mureșan, Cătană Andreea, Popp Radu Anghel, Dumitraș Diana Elena, Stamatian Florin, Buzoianu Anca Dana, Rotar Ioana Cristina   +6 more
doaj   +1 more source

Glutathione transferases in soybean glycine max (L.) Merr [PDF]

, 1999
Glutathione transferases, also known as Glutathione S-transferases (GSTs), are a diverse group of enzymes that catalyse the conjugation of the tri-peptide glutathione to a wide range of electrophilic substrates.
Andrews, Christopher John
core  

Glutathione transferases in maize (zea mays) [PDF]

, 1998
The glutathione transferases (GSTs) of maize have been the most studied GSTs in plants, however much is still not known about these enzymes. In the course of the current study six GST subunits (Zm GSTs I, II and III, which have been reported previously ...
Dixon, D.P., Dixon, David Peter
core  

Glutathione S transferase polymorphisms influence on iron overload in β-thalassemia patients

Thalassemia Reports, 2013
In patients with β-thalassemia iron overload that leads to damage to vital organs is observed. Glutathione S transferase (GST) enzymes have an antioxidant role in detoxification processes of toxic substances. This role is determined genetically.
Serena Sclafani, Giuseppina Calvaruso, Veronica Agrigento, Aurelio Maggio, Valeria Lo Nigro, Elena D’Alcamo   +5 more
doaj   +1 more source

Role of glutathione transferases in herbicide detoxification in weeds [PDF]

, 1996
Glutathione transferases (GSTs) catalyse the conjugation of the electrophilic herbicides atrazine, metolachlor, alachlor and fluorodifen with the tripeptide glutathione (GSH).
Hatton, Pamela J., Hatton, P.J.
core  

Crystal structure of a murine α-class glutathione S-transferase involved in cellular defense against oxidative stress [PDF]

, 1998
Glutathione S-transferases (GSTs) are ubiquitous multifunctional enzymes which play a key role in cellular detoxification. The enzymes protect the cells against toxicants by conjugating them to glutathione.
Klaus-Hasso Schröter, Schröter, Klaus-Hasso, Bauke W Dijkstra, Anita Arkema, Arkema, Anita,, Dijkstra, Bauke W., Schröter, Klaus-Hasso,, Arkema, Anita, Zimniak, Piotr, Krengel, Ute, Dijkstra, Bauke W, Krengel, Ute,, Kalk, Kor H., Kalk, Kor H.,, Piotr Zimniak, Dijkstra, Bauke W.,, Hoier, Helga,, Helga Hoier, Hoier, Helga, Kalk, Kor H, Ute Krengel, Kor H Kalk, Zimniak, Piotr,   +22 more
core   +1 more source

Characterization of the Omega Class of Glutathione Transferases

, 2015
The Omega class of cytosolic glutathione transferases was initially recognized by bioinformatic analysis of human sequence databases, and orthologous sequences were subsequently discovered in mouse, rat, pig, Caenorhabditis elegans, Schistosoma mansoni ...
Whitbread, Astrid, Masoumi, Amir, Board, Philip, Tetlow, Natasha, Coggan, Marjorie, Schmuck, Erica   +5 more
core   +1 more source

Evolutionary conservation of regulated longevity assurance mechanisms [PDF]

, 2007
Background: To what extent are the determinants of aging in animal species universal? Insulin/ insulin-like growth factor ( IGF)-1 signaling ( IIS) is an evolutionarily conserved ( public) regulator of longevity; yet it remains unclear whether the genes ...
Linda Partridge, Piper, Matthew D., David Gems, Schuster, E, Piper, MD, Gems, D, McElwee, J.J., Thomas, J.H., Partridge, L., Joshua J McElwee, Withers, D.J., McElwee, JJ, Patel, DS, Dhaval S Patel, Thornton, J.M., Blanc, E, Matthew D Piper, McElwee, J.J, Patel, Dhaval S., Withers, Dominic J., Schuster, E., Dominic J Withers, Janet M Thornton, Selman, C, Withers, DJ, Thorton, Janet M., Selman, C., Eugene Schuster, Selman, Colin, Partridge, Linda, Piper, M.D., Blanc, Eric, Thomas, JH, Eric Blanc, Patel, D, McElwee, Joshua J., Gems, D., James H Thomas, Partridge, L, Blanc, E., Thornton, JM, Gems, David, Schuster, Eugene, Thomas, J H, Colin Selman, Piper, M D, Patel, D.S., Thomas, James H.   +47 more
core   +1 more source