Results 31 to 40 of about 21,521,606 (315)

BENZYLIDENE CYCLOPENTANONE DERIVATIVES AS INHIBITORS OF RAT LIVER GLUTATHIONE S-TRANSFERASE ACTIVITIES

open access: yesIndonesian Journal of Chemistry, 2010
The effect of the curcumin analogues, 2,6-bis-(4-hydroxy-3-methoxy benzylidene) cyclopentanone (B1) and two of its derivatives on m class glutathione S-transferases (GSTs) from phenobarbital-induced and uninduced rat liver cytosol has been studied to ...
Sudibyo Martono
doaj   +1 more source

Glutathione transferase gene polymorphism in end stage renal disease [PDF]

open access: yesMedicinski Podmladak, 2016
Chronic kidney disease is described as a progressive and irreversible deterioration in kidney function. When there is less than 10% of nephron function pertained, patients face end-stage renal disease, where renal replacement therapy is needed. Data show
Šuvakov Sonja   +2 more
doaj   +1 more source

Genetic Polymorphisms of Glutathione S-Transferases T1 (GSTT1) and M1 (GSTM1) in Iranian Mandaeans Population

open access: yesIranian Journal of Public Health, 2019
Genetic Polymorphisms of Glutathione S-Transferases T1 (GSTT1) and M1 (GSTM1) in Iranian Mandaeans ...
Fariba BOROUMAND   +2 more
doaj   +1 more source

Protein engineering to probe the catalytic mechanism of Alpha-class glutathione S-transferases

open access: yes, 1997
Glutathione S-Transferases (GSTs) are a large family of isoenzymes that catalyse the addition of glutathione to hydrophobic electrophiles. Over-expression of GSTs in tumours leads to resistance to chemotherapy drugs, thus understanding GST biochemistry ...
Paul David. McDonagh (7656347)
core   +6 more sources

The multifaceted role of glutathione S-transferases in cancer.

open access: yesCancer Letters, 2018
Glutathione S-transferases (GSTs) are phase II detoxifying enzymes involved in the maintenance of cell integrity, oxidative stress and protection against DNA damage by catalyzing the conjugation of glutathione to a wide variety of electrophilic ...
A. Chatterjee, Sanjay Gupta
semanticscholar   +1 more source

RsGSTF12 Contributes to Anthocyanin Sequestration in Radish (Raphanus sativus L.)

open access: yesFrontiers in Plant Science, 2022
Anthocyanins are water-soluble plant pigments mainly stored in the plant vacuoles. Glutathione S-transferases (GSTs) are a multifunctional enzyme family, which can regulate substance metabolism and biological and abiotic stresses in plants.
Mengyang Niu   +7 more
doaj   +1 more source

Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation

open access: yesScience Signaling, 2019
Glutathione S-transferases in astrocytes enhance microglia activation during brain inflammation. Glutathione S-transferases enhance astrocyte-microglia communication Astrocytes and microglia contribute to inflammatory responses in the brain.
S. Kano   +10 more
semanticscholar   +1 more source

Allyl isothiocyanate depletes glutathione and upregulates expression of glutathione S-transferases in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2015
Allyl isothiocyanate (AITC) is a phytochemical associated with plant defense in plants from the Brassicaceae family. AITC has long been recognized as a countermeasure against external threats, but recent reports suggest that AITC is also involved in the ...
Anders eØverby   +4 more
doaj   +1 more source

Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast. [PDF]

open access: yesPLoS ONE, 2018
Heavy metal and metalloid contaminations are among the most concerning types of pollutant in the environment. Consequently, it is important to investigate the molecular mechanisms of cellular responses and detoxification pathways for these compounds in ...
Houman Moteshareie   +19 more
doaj   +1 more source

GSTP1 and GSTM3 Variant Alleles Affect Susceptibility and Severity of COVID-19

open access: yesFrontiers in Molecular Biosciences, 2021
Based on the premise that oxidative stress plays an important role in severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection, we speculated that variations in the antioxidant activities of different members of the glutathione S-transferase ...
Vesna Coric   +27 more
doaj   +1 more source

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