Results 261 to 270 of about 428,300 (333)

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Glutathione Transferase P1 Polymorphism Might Be a Risk Determinant in Heart Failure. [PDF]

Dis Markers, 2019
Simeunovic D, Odanovic N, Pljesa-Ercegovac M, Radic T, Radovanovic S, Coric V, Milinkovic I, Matic M, Djukic T, Ristic A, Risimic D, Seferovic P, Simic T, Simic D, Savic-Radojevic A.   +14 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Metabolo‐Transcriptomics Analyses Reveal Alfalfa Adaptation to Combined Saline‐Alkali and Low‐Temperature Stress in the Field

Plant Biotechnology Journal, EarlyView.
ABSTRACT Alfalfa (Medicago sativa L.) is known as the ‘King of Forage’ because of its high protein content and excellent palatability. Alfalfa productivity is adversely affected in cold regions with saline‐alkali soils. However, the mechanisms underlying the response of alfalfa to combined saline‐alkali and low‐temperature stress under field conditions
Rui Guo, Lei Liu, Jiaqi Li, Hongyu Qu, Weileng Guo, Lishuang Zhang, Dihe Yang, Ruixin Wang, Changhong Guo   +8 more
wiley   +1 more source

Metabolomic and Single‐Cell Transcriptomic Analyses Shed Light on Secondary Metabolite Profiling and Potential Developmental Dynamics of Glandular Trichomes in Artemisia argyi

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant glandular trichomes (GTs) are characterised by their ability to synthesise and store abundant secondary metabolites of significant biological importance. The medicinal plant Artemisia argyi exhibits a dense covering of GTs, yet the precise metabolic compositions and the developmental molecular dynamics of A.
Shuting Dong, Hongyu Chen, Sijie Sun, Miaoxian Guo, Chao Sun, Shilin Chen, Hongmei Luo   +6 more
wiley   +1 more source

A Glutathione S-Transferase Pi Molecular Glue Tethers Splicing Factors and Remodels Cell Metabolism

David M. Leace, Madeleine L. Ware, Olivia Murtagh, Hsiao-Kuei Tsai, Chin‐Yuan Chang, Ku‐Lung Hsu   +5 more
openalex   +2 more sources

Overexpression of a Tonoplast Malate Transporter Gene Leads to Enhanced Anthocyanin Biosynthesis in Apple

Plant Biotechnology Journal, EarlyView.
ABSTRACT Anthocyanins, a group of secondary metabolites synthesised in the phenylpropanoid pathway, largely determine the peel colour of fleshy fruits, but it is not known if their synthesis is linked to vacuolar malate accumulation that underlies fruit acidity.
Mengxia Zhang, Jiahao Zhao, Nan Wang, Da‐Gang Hu, Ewa Borejsza‐Wysocka, Lailiang Cheng   +5 more
wiley   +1 more source

Calmodulin‐Like Protein MfCML50 Interacts With Carveol Dehydrogenase in Medicago falcata to Regulate Cold Tolerance Through Mediating ROS Homeostasis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Low temperature triggers Ca2+ signalling and reprogramming of gene expression and metabolism in plants. However, how the Ca2+ signal is transduced to the downstream metabolic pathways remains unknown. The involvement of a cold‐induced calmodulin‐like protein, MfCML50, from Medicago falcata in regulation of cold tolerance was examined in the ...
Bohao Geng, Shuhan Yu, Qiguo Sun, Lei Yang, Qian Yang, Hailong Yang, Zhenfei Guo   +6 more
wiley   +1 more source

The RNA m6A Methyltransferase PvFIP37 Activates Vacuole Transport and Glutathione Detoxification Pathways to Increase Switchgrass Cd Tolerance

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cadmium (Cd) pollution is a growing global issue that poses significant threats to ecosystems and human health. N6‐methyladenosine (m6A) plays an essential role in regulating plant growth and stress responses, but the biological functions and regulatory mechanisms of m6A core enzymes under Cd stress remain largely unexplored. In this study, we
Mengzhuo Lin, Lei Wang, Bowen Liu, Huayue Liu, Wenwu Qian, Die Zhou, Hui Zang, Binglin Hong, Yunwei Zhang, Jishan Jiang   +9 more
wiley   +1 more source

VvERF045 Integrates Ethylene, Brassinosteroid and Abscisic Acid Pathways to Orchestrate Anthocyanin Biosynthesis in Grapevine

Plant Biotechnology Journal, EarlyView.
ABSTRACT Anthocyanin biosynthesis in non‐climacteric grape berries is regulated through coordinated phytohormonal signalling networks. However, the precise mechanisms by which abscisic acid (ABA), brassinosteroids (BRs) and ethylene (ET) synergistically modulate this process remain unclear.
Jiajia Li, Qifei Gao, Yi Quan, Ruo he Yin, Boyang Liu, Yang Hu, Song tao Jiu, Bin Han, Ying Zhang, Jiayu Han, Shuli Han, Dinghan Guo, Chao Ma, Caixi Zhang, Lei Wang, Shiping Wang   +15 more
wiley   +1 more source