Expression of Heterologous OsDHAR Gene Improves Glutathione (GSH)-Dependent Antioxidant System and Maintenance of Cellular Redox Status in Synechococcus elongatus PCC 7942. [PDF]
, 2020 An excess of reactive oxygen species (ROS) can cause severe oxidative damage to cellular components in photosynthetic cells. Antioxidant systems, such as the glutathione (GSH) pools, regulate redox status in cells to guard against such damage ...
Beld, Joris +9 more
core +2 more sources
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Genetic polymorphisms of glutathione S transferase and cervical intraepithelial neoplasia
Romanian Journal of Laboratory Medicine, 2016 Aim: The present study aim to analyze the relationship between GST M/T genotypes of glutathione S-transferases and cervical intraepithelial neoplasia.
Daniel Mureșan +6 more
doaj +1 more source
International Journal of Preventive Medicine, 2017 Epidemiological evidence on the association between genetic polymorphisms in glutathione S-transferases M1 (GSTM1) and T1 (GSTT1) genes and risk of endometrial cancer (EC) has been inconsistent.
Xiuxiu Yin, Jie Chen
doaj +1 more source
Toxicity induced by Solanapyrone A in Chickpea shoots and its metabolism through Glutathione/Glutathione-S-Transferase system [PDF]
, 2013 Solanapyrone A and C were isolated from a Pakistani isolate of Ascochyta rabiei, Pk-1. Two experiments were conducted to investigate the phytotoxic effects of the most potent toxin, solanapyrone A on chickpea cultivars and its subsequent detoxification ...
Abdur Rauf, C. +5 more
core
Transcriptomic footprints disclose specificity of reactive oxygen species signaling in Arabidopsis [PDF]
, 2006 Reactive oxygen species ( ROS) are key players in the regulation of plant development, stress responses, and programmed cell death. Previous studies indicated that depending on the type of ROS ( hydrogen peroxide, superoxide, or singlet oxygen) or its ...
Apel, Klaus +9 more
core +4 more sources
Urinary felinine excretion in intact male cats is increased by dietary cystine [PDF]
, 2008 Felinine is a branched-chain sulfur amino acid present in the urine of certain Felidae, including domestic cats. The objective of the present study was to determine if additional cystine and/or dietary N would increase felinine and N-acetylfelinine ...
Hendriks, W.H. +4 more
core +2 more sources
The still mysterious roles of cysteine-containing glutathione transferases in plants
Frontiers in Pharmacology, 2014 Glutathione transferases (GSTs) represent a widespread multigenic enzyme family able to modify a broad range of molecules. These notably include secondary metabolites and exogenous substrates often referred to as xenobiotics, usually for their ...
Pierre-Alexandre eLallement +7 more
doaj +1 more source
GSTP1 and GSTM3 Variant Alleles Affect Susceptibility and Severity of COVID-19
Frontiers in Molecular Biosciences, 2021 Based on the premise that oxidative stress plays an important role in severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection, we speculated that variations in the antioxidant activities of different members of the glutathione S-transferase ...
Vesna Coric +27 more
doaj +1 more source
Catalytic and structural diversity of the fluazifop-inducible glutathione transferases from Phaseolus vulgaris [PDF]
, 2011 Plant glutathione transferases (GSTs) comprise a large family of inducible enzymes that play important roles in stress tolerance and herbicide detoxification.
Asimakopoulou, Basiliki +5 more
core +2 more sources