Results 51 to 60 of about 46,208 (193)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapyinduced leukemia [PDF]

, 2001
Glutathione S-transferases (GSTs) detoxify potentially mutagenic and toxic DNA-reactive electrophiles, including metabolites of several chemotherapeutic agents, some of which are suspected human carcinogens.
Akande, Ban, Brusamolino, Czerwinski, Czerwinski, Diamandidou, Dirven, Felix, Felix, Fisher, Gerson, GREENE, Grimwade, Harries, Johansson, Johansson, Kaldor, Kaldor, Kane, Kuga, Larson, Le Beau, Matsunaga, Miyazaki, Nakagawa, Naoe, O'Brien, Pandya, Panizo, Pearson, Pedersen-Bjergaard, Rivera, Rollinson, Roth, Ryberg, Sasai, Seidegard, Skibola, Sprenger, Srivastava, Sweeney, Tan, Travis, Travis, Travis, Watson, WILSON, Wolden, Woo, Zimniak   +49 more
core   +7 more sources

Diversification of fungal specific class a glutathione transferases in saprotrophic fungi. [PDF]

PLoS ONE, 2013
Glutathione transferases (GSTs) form a superfamily of multifunctional proteins with essential roles in cellular detoxification processes and endogenous metabolism.
Yann Mathieu, Pascalita Prosper, Frédérique Favier, Luc Harvengt, Claude Didierjean, Jean-Pierre Jacquot, Mélanie Morel-Rouhier, Eric Gelhaye   +7 more
doaj   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

The Isolation and Identification of Anthocyanin-Related GSTs in Chrysanthemum

Horticulturae, 2021
Anthocyanin is the crucial pigment for the coloration of red chrysanthemum flowers, which synthesizes in the cytosol and is transported to the vacuole for stable storage.
Yajing Li, Xiaofen Liu, Fang Li, Lili Xiang, Kunsong Chen   +4 more
doaj   +1 more source

Acetaminophen detoxification in cucumber plants via induction of glutathione S-transferases. [PDF]

, 2019
Many pharmaceutical and personal care products (PPCPs) enter agroecosystems during reuse of treated wastewater and biosolids, presenting potential impacts on plant development.
Dudley, Stacia, Gan, Jay, McGinnis, Michelle, Sun, Chengliang, Trumble, John   +4 more
core  

Pharmaceutical and personal care products-induced stress symptoms and detoxification mechanisms in cucumber plants. [PDF]

, 2018
Contamination of agricultural soils by pharmaceutical and personal care products (PPCPs) resulting from the application of treated wastewater, biosolids and animal wastes constitutes a potential environmental risk in many countries.
Dudley, Stacia, Gan, Jay, Sun, Chengliang, Trumble, John   +3 more
core   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes [PDF]

, 2008
A retrospective study on healthy, unrelated subjects was conducted in order to estimate population glutathione-S-transferases (GST) genotype frequencies in Slovak population of men and compare our results with already published data (GSEC project)^1^.
Duš, Iveta Waczulí, Já, Jozef Hatok, Monika Sivoň, Peter Rač, Tatiana Matá   +6 more
core   +1 more source

Regulation of plasmid-encoded isoprene metabolism in Rhodococcus, a representative of an important link in the global isoprene cycle [PDF]

, 2015
Emissions of biogenic volatile organic compounds (VOCs) form an important part of the global carbon cycle, comprising a significant proportion of net ecosystem productivity.
Crombie, Andrew T., Fengler, Kevin A., Khawand, Myriam El, Mcgenity, Terry J., Miller, Michael C., Murrell, J. Colin, Rhodius, Virgil A., Whited, Gregg M.   +7 more
core   +1 more source