Communications Biology, 2022 Transcriptome profiling and mutational analysis suggest a potential deficiency in anthocyanin transport by glutathione S-transferases and/or degradation mechanisms that might cause unpigmented berries.
Ahmed Ismail +7 more
doaj +1 more source
Forager bees (Apis mellifera) highly express immune and detoxification genes in tissues associated with nectar processing. [PDF]
, 2015 Pollinators, including honey bees, routinely encounter potentially harmful microorganisms and phytochemicals during foraging. However, the mechanisms by which honey bees manage these potential threats are poorly understood.
Johnson, Brian R +2 more
core +1 more source
The role of glutathione transferases in renal cell carcinoma [PDF]
Medicinski Podmladak, 2016 Mounting evidence suggest that members of the subfamily of cytosolic glutathione S-transferases (GSTs) possess roles far beyond the classical glutathione-dependent enzymatic conjugation of electrophilic metabolites and xenobiotics.
Ćorić Vesna +2 more
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The Glutathione System: A Journey from Cyanobacteria to Higher Eukaryotes
Antioxidants, 2023 From bacteria to plants and humans, the glutathione system plays a pleiotropic role in cell defense against metabolic, oxidative and metal stresses. Glutathione (GSH), the γ-L-glutamyl-L-cysteinyl-glycine nucleophile tri-peptide, is the central player of
Corinne Cassier-Chauvat +4 more
doaj +1 more source
Degradation of lignin β-aryl ether units in Arabidopsis thaliana expressing LigD, LigF and LigG from Sphingomonas paucimobilis SYK-6 [PDF]
, 2017 Lignin is a major polymer in the secondary plant cell wall and composed of hydrophobic interlinked hydroxyphenylpropanoid units. The presence of lignin hampers conversion of plant biomass into biofuels; plants with modified lignin are therefore being ...
Bent +61 more
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Glutathione Transferases: Potential Targets to Overcome Chemoresistance in Solid Tumors. [PDF]
Int J Mol Sci, 2018 Pljesa-Ercegovac M +6 more
europepmc +2 more sources
Transcriptome profiling of a spirodiclofen susceptible and resistant strain of the European red mite Panonychus ulmi using strand-specific RNA-seq [PDF]
, 2015 Background: The European red mite, Panonychus ulmi, is among the most important mite pests in fruit orchards, where it is controlled primarily by acaricide application.
Bajda, Sabina +6 more
core +17 more sources
Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]
, 2019 A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
core +2 more sources
MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation. [PDF]
, 2018 We show for the first time that, in contrast to other glutathione transferases and peroxidases, deletion of microsomal glutathione transferase 1 (MGST1) in mice is embryonic lethal.
Abe, Hiroshi +10 more
core +3 more sources
Regulation of Signal Transduction by Glutathione Transferases
International Journal of Hepatology, 2012 Glutathione transferases (GST) are essentially known as enzymes that catalyse the conjugation of glutathione to various electrophilic compounds such as chemical carcinogens, environmental pollutants, and antitumor agents.
Julie Pajaud +4 more
doaj +1 more source