Results 11 to 20 of about 46,208 (193)

Glutathione S-Transferases in Cancer

Antioxidants, 2021
In humans, the glutathione S-transferases (GST) protein family is composed of seven members that present remarkable structural similarity and some degree of overlapping functionalities.
Rahul Raj Singh, Katie M. Reindl
doaj   +3 more sources

Structural and Thermodynamic Insights into Dimerization Interfaces of Drosophila Glutathione Transferases. [PDF]

Biomolecules
This study presents a comprehensive analysis of the dimerization interfaces of fly GSTs through sequence alignment. Our investigation revealed GSTE1 as a particularly intriguing target, providing valuable insights into the variations within Delta and ...
Schwartz M, Petiot N, Chaloyard J, Senty-Segault V, Lirussi F, Senet P, Nicolai A, Heydel JM, Canon F, Sonkaria S, Khare V, Didierjean C, Neiers F.   +12 more
europepmc   +2 more sources

Editorial: The expanding functional network of glutathione transferases. [PDF]

Front Mol Biosci, 2023
Piaggi S, Diederich M, Corti A.
europepmc   +2 more sources

Kinetic Behavior of Glutathione Transferases: Understanding Cellular Protection from Reactive Intermediates [PDF]

Biomolecules
Glutathione transferases (GSTs) are the primary catalysts protecting from reactive electrophile attack. In this review, the quantitative levels and distribution of glutathione transferases in relation to physiological function are discussed.
Ralf Morgenstern
europepmc   +2 more sources

Characterization of rat glutathione transferases in olfactory epithelium and mucus. [PDF]

PLoS One, 2019
The olfactory epithelium is continuously exposed to exogenous chemicals, including odorants. During the past decade, the enzymes surrounding the olfactory receptors have been shown to make an important contribution to the process of olfaction.
Heydel JM, Menetrier F, Belloir C, Canon F, Faure P, Lirussi F, Chavanne E, Saliou JM, Artur Y, Canivenc-Lavier MC, Briand L, Neiers F.   +11 more
europepmc   +2 more sources

Functional, Structural and Biochemical Features of Plant Serinyl-Glutathione Transferases. [PDF]

Front Plant Sci, 2019
Glutathione transferases (GSTs) belong to a ubiquitous multigenic family of enzymes involved in diverse biological processes including xenobiotic detoxification and secondary metabolism.
Sylvestre-Gonon E, Law SR, Schwartz M, Robe K, Keech O, Didierjean C, Dubos C, Rouhier N, Hecker A.   +8 more
europepmc   +2 more sources

The catalytic role of glutathione transferases in heterologous anthocyanin biosynthesis. [PDF]

Nat Catal, 2023
Eichenberger M, Schwander T, Hüppi S, Kreuzer J, Mittl PRE, Peccati F, Jiménez-Osés G, Naesby M, Buller RM.   +8 more
europepmc   +2 more sources

Glutathione S-Transferases in Marine Copepods

Journal of Marine Science and Engineering, 2021
The glutathione S-transferase (GST) is a complex family of phase II detoxification enzymes, known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to a wide variety of endogenous and exogenous electrophilic compounds
Chiara Lauritano, Ylenia Carotenuto, Vittoria Roncalli   +2 more
doaj   +1 more source

Analysis of the olive fruit fly Bactrocera oleae transcriptome and phylogenetic classification of the major detoxification gene families [PDF]

, 2013
he olive fruit fly Bactrocera oleae has a unique ability to cope with olive flesh, and is the most destructive pest of olives worldwide. Its control has been largely based on the use of chemical insecticides, however, the selection of insecticide ...
Antonios Chrysargyris, Antonis Chrisargiris, John Vontas, Nena Pavlidi, Stephane Rombauts, Thomas Van Leeuwen, Wannes Dermauw   +6 more
core   +11 more sources

Versatility of Glutathione Transferase Proteins

Biomolecules, 2023
For more than 60 years, glutathione transferases (GSTs) have attracted attention, but the research field of the GSTome [...]
Bengt Mannervik
doaj   +1 more source