Plasmodium spp. membrane glutathione S-transferases: detoxification units and drug targets
Microbial Cell, 2014 Membrane glutathione S-transferases from the class of membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG) form a superfamily of detoxification enzymes that catalyze the conjugation of reduced glutathione (GSH) to a broad ...
Andreas Martin Lisewski
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Structural and Thermodynamic Insights into Dimerization Interfaces of Drosophila Glutathione Transferases [PDF]
BiomoleculesThis study presents a comprehensive analysis of the dimerization interfaces of fly GSTs through sequence alignment. Our investigation revealed GSTE1 as a particularly intriguing target, providing valuable insights into the variations within Delta and ...
Mathieu Schwartz +12 more
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Editorial: The expanding functional network of glutathione transferases [PDF]
Frontiers in Molecular Biosciences, 2023 Simona Piaggi +2 more
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Characterization of rat glutathione transferases in olfactory epithelium and mucus. [PDF]
PLoS ONE, 2019 The olfactory epithelium is continuously exposed to exogenous chemicals, including odorants. During the past decade, the enzymes surrounding the olfactory receptors have been shown to make an important contribution to the process of olfaction.
Jean-Marie Heydel +11 more
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Functional, Structural and Biochemical Features of Plant Serinyl-Glutathione Transferases [PDF]
Frontiers in Plant Science, 2019 Glutathione transferases (GSTs) belong to a ubiquitous multigenic family of enzymes involved in diverse biological processes including xenobiotic detoxification and secondary metabolism.
Elodie Sylvestre-Gonon +8 more
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Toxicity induced by Solanapyrone A in Chickpea shoots and its metabolism through Glutathione/Glutathione-S-Transferase system [PDF]
, 2013 Solanapyrone A and C were isolated from a Pakistani isolate of Ascochyta rabiei, Pk-1. Two experiments were conducted to investigate the phytotoxic effects of the most potent toxin, solanapyrone A on chickpea cultivars and its subsequent detoxification ...
Riaz, A. +5 more
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Glutathione S-Transferases in Cancer
Antioxidants, 2021 In humans, the glutathione S-transferases (GST) protein family is composed of seven members that present remarkable structural similarity and some degree of overlapping functionalities.
Rahul Raj Singh, Katie M. Reindl
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The active site in class alpha glutathione transferases
, 1993 Sinning, I, +4 more
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The role of glutathione transferases in TNT detoxification [PDF]
, 2012 Glutathione transferases (GSTs) are multi-functional enzymes with an important role in plant biochemical mechanisms of xenobiotic detoxification. The GSTs have been extensively studied due to their ability to detoxify herbicides; recently they have been ...
Gunning, Vanda
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Glutathione S-Transferases in Marine Copepods
Journal of Marine Science and Engineering, 2021 The glutathione S-transferase (GST) is a complex family of phase II detoxification enzymes, known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to a wide variety of endogenous and exogenous electrophilic compounds
Chiara Lauritano +2 more
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